(Q41553559)

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Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system

scientific article published on February 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system (English)

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

0 references

Reinhard Georg Lührmann

8

object named as

Reinhard Lührmann

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

4

object named as

Henning Urlaub

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

author name string

Jean-Baptiste Fourmann

1

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Jana Schmitzová

2

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Henning Christian

3

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Ralf Ficner

5

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Kum-Loong Boon

6

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Patrizia Fabrizio

7

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

publication date

1 February 2013

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Europe PubMed Central

PMC publication ID

3 October 2017

Genes & Development

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Europe PubMed Central

PMC publication ID

3 October 2017

27

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

413-428

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

CWC22 connects pre-mRNA splicing and exon junction complex assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Structure, function and regulation of spliceosomal RNA helicases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The mechanism of the second step of pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Cwc25 is a novel splicing factor required after Prp2 and Yju2 to facilitate the first catalytic reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Inhibition of a spliceosome turnover pathway suppresses splicing defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Exon ligation is proofread by the DExD/H-box ATPase Prp22p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The Prp19p-associated complex in spliceosome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Characterization of interactions among the Cef1p-Prp19p-associated splicing complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Mechanical devices of the spliceosome: motors, clocks, springs, and things

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Prp43: An RNA helicase-like factor involved in spliceosome disassembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

6 June 2018

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

19 August 2018

The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

19 August 2018

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

19 August 2018

Requirement for SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3' splice site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589558

19 August 2018

Identifiers

10.1101/GAD.207779.112

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

ResearchGate publication ID

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