(Q41640484)

5 October 2017

1 reference

title

p53 tumor-suppressor gene: clues to molecular carcinogenesis (English)

1 reference

5 October 2017

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Wang XW

1

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5 October 2017

Harris CC

series ordinal

2

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5 October 2017

publication date

1 November 1997

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Journal of Cellular Physiology

5 October 2017

published in

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5 October 2017

volume

173

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5 October 2017

issue

2

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5 October 2017

page(s)

247-255

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T antigen is bound to a host protein in SY40-transformed cells

5 October 2017

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Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

21 January 2018

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Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.

21 January 2018

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Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung

21 January 2018

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Genetic alterations during colorectal-tumor development

21 January 2018

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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

21 January 2018

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p53: a frequent target for genetic abnormalities in lung cancer.

21 January 2018

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Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung

21 January 2018

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Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia

21 January 2018

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Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

21 January 2018

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Wild-type p53 can inhibit oncogene-mediated focus formation

21 January 2018

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The p53 proto-oncogene can act as a suppressor of transformation

21 January 2018

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Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

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p53 functions as a cell cycle control protein in osteosarcomas

21 January 2018

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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

21 January 2018

1 reference

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Genetic mechanisms of tumor suppression by the human p53 gene

21 January 2018

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p53 mutations in human cancers

21 January 2018

1 reference

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Multifactorial analysis of p53 alteration in human cancer: a review

21 January 2018

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21 January 2018

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Oncogenic forms of p53 inhibit p53-regulated gene expression

21 January 2018

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

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Presence of a potent transcription activating sequence in the p53 protein

21 January 2018

1 reference

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Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

21 January 2018

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The MCK enhancer contains a p53 responsive element

21 January 2018

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Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

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Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

21 January 2018

1 reference

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Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

A transcriptionally active DNA-binding site for human p53 protein complexes

21 January 2018

1 reference

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

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Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

21 January 2018

1 reference

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Mammalian p53 can function as a transcription factor in yeast

21 January 2018

1 reference

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Isolation and characterization of DNA sequences that are specifically bound by wild-type p53 protein

21 January 2018

1 reference

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

21 January 2018

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p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.

21 January 2018

1 reference

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Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

21 January 2018

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A p53-dependent mouse spindle checkpoint

21 January 2018

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p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

21 January 2018

1 reference

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Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

21 January 2018

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Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines

21 January 2018

1 reference

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

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Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

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Wild-type p53 binds to the TATA-binding protein and represses transcription

21 January 2018

1 reference

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The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

21 January 2018

1 reference

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Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation

21 January 2018

1 reference

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p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

21 January 2018

1 reference

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Human TAFII31 protein is a transcriptional coactivator of the p53 protein

21 January 2018

1 reference

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Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

21 January 2018

1 reference

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Wild-type p53 can down-modulate the activity of various promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

21 January 2018

1 reference

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Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression

21 January 2018

1 reference

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Negative regulation of Rb expression by the p53 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Repression of the basal c-fos promoter by wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

The tumor suppressor p53 regulates its own transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Inhibition of DNA replication factor RPA by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

The transactivator proteins VP16 and GAL4 bind replication factor A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

p53 modulation of TFIIH-associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Physical and functional interaction between WT1 and p53 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

21 January 2018

1 reference

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21 January 2018

1 reference

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Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

21 January 2018

1 reference

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Correction of xeroderma pigmentosum complementation group D mutant cell phenotypes by chromosome and gene transfer: involvement of the human ERCC2 DNA repair gene

21 January 2018

1 reference

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ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

21 January 2018

1 reference

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

21 January 2018

1 reference

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p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

1 reference

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

21 January 2018

1 reference

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Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

21 January 2018

1 reference

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

1 reference

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

21 January 2018

1 reference

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

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The p53 tumour suppressor gene

21 January 2018

1 reference

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p53 mutations increase resistance to ionizing radiation

21 January 2018

1 reference

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Growth factor modulation of p53-mediated growth arrest versus apoptosis

21 January 2018

1 reference

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

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Programmed cell death and the control of cell survival: lessons from the nervous system

21 January 2018

1 reference

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

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Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

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The Bloom's syndrome gene product is homologous to RecQ helicases

21 January 2018

1 reference

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

21 January 2018

1 reference

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Transcriptional activation by p53 correlates with suppression of growth but not transformation.

21 January 2018

1 reference

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Essential role for p53-mediated transcription in E1A-induced apoptosis

21 January 2018

1 reference

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Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

1 reference

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

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Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

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Apoptotic cell death induced by c-myc is inhibited by bcl-2.

21 January 2018

1 reference

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

21 January 2018

1 reference

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Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

21 January 2018

1 reference

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p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

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p53-mediated cell death: relationship to cell cycle control

21 January 2018

1 reference

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Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53.

21 January 2018

1 reference

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The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

21 January 2018

No room at the p53 inn

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28199711%29173%3A2%3C247%3A%3AAID-JCP30%3E3.0.CO%3B2-A

10.1002/(SICI)1097-4652(199711)173:2<247::AID-JCP30>3.0.CO;2-A

21 January 2018

Identifiers

DOI

1 reference

5 October 2017

1 reference