(Q41720317)

8 October 2017

title

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing (English)

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8 October 2017

author

Victor M Bolanos-Garcia

series ordinal

4

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8 October 2017

5

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8 October 2017

Tiziana Lischetti

1

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Gang Zhang

object named as

Gang Zhang

series ordinal

2

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author name string

Garry G Sedgwick

series ordinal

3

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8 October 2017

language of work or name

English

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publication date

8 December 2014

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8 October 2017

published in

Nature Communications

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8 October 2017

volume

5

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8 October 2017

page(s)

5563

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https://scigraph.springernature.com/pub.10.1038/ncomms6563

8 October 2017

exact match

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cites work

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Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

21 January 2018

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

21 January 2018

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Cubism and the cell cycle: the many faces of the APC/C.

21 January 2018

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Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.

21 January 2018

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Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

21 January 2018

1 reference

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Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

21 January 2018

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

21 January 2018

1 reference

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The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

21 January 2018

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Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding

21 January 2018

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Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.

21 January 2018

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MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p

21 January 2018

1 reference

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The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.

21 January 2018

1 reference

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Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

21 January 2018

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Structure of the mitotic checkpoint complex

21 January 2018

1 reference

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BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex

21 January 2018

1 reference

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p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.

21 January 2018

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Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint

21 January 2018

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The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

21 January 2018

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Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint

21 January 2018

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Structural analysis of human Cdc20 supports multisite degron recognition by APC/C

21 January 2018

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Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1.

21 January 2018

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BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase

21 January 2018

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Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy.

21 January 2018

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Timing and checkpoints in the regulation of mitotic progression

21 January 2018

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Spindle checkpoint protein dynamics at kinetochores in living cells.

21 January 2018

1 reference

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Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells

21 January 2018

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Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing

21 January 2018

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Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6563

21 January 2018

Identifiers

DOI

10.1038/NCOMMS6563

1 reference

Dimensions Publication ID

8 October 2017

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1052677715

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1 reference