(Q42152333)

17 October 2017

Determinants of amyloid fibril degradation by the PDZ protease HTRA1. (English)

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17 October 2017

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17 October 2017

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17 October 2017

Michael Ehrmann

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Christos Gatsogiannis

object named as

Christos Gatsogiannis

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author name string

Simon Poepsel

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17 October 2017

Andreas Sprengel

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17 October 2017

Barbara Sacca

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17 October 2017

Farnusch Kaschani

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17 October 2017

Markus Kaiser

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17 October 2017

5 October 2015

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17 October 2017

Nature Chemical Biology

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17 October 2017

11

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17 October 2017

862-869

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17 October 2017

11

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https://scigraph.springernature.com/pub.10.1038/nchembio.1931

17 October 2017

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cites work

Towards revealing the structure of bacterial inclusion bodies

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Aggregation of amyloids in a cellular context: modelling and experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Heat shock factors: integrators of cell stress, development and lifespan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Chaperone machines for protein folding, unfolding and disaggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The HtrA Family of Proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

HTRA proteases: regulated proteolysis in protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Substrate-induced remodeling of the active site regulates human HTRA1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Serine protease HtrA1 associates with microtubules and inhibits cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The emerging roles of HTRA1 in musculoskeletal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The role of human HtrA1 in arthritic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

HtrA serine proteases as potential therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Implications of the serine protease HtrA1 in amyloid precursor protein processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Emerging roles of serine proteinases in tissue turnover in arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Tau pathology and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Straight and paired helical filaments in Alzheimer disease have a common structural unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Structural polymorphism of 441-residue tau at single residue resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Structural and functional analysis of HtrA1 and its subdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The autolysis of human HtrA1 is governed by the redox state of its N-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

ATP-independent reversal of a membrane protein aggregate by a chloroplast SRP subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Structural basis for the regulated protease and chaperone function of DegP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Chaperones increase association of tau protein with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

The spread of neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

NIH Image to ImageJ: 25 years of image analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

A pyramid approach to subpixel registration based on intensity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Ultra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Probability-based protein identification by searching sequence databases using mass spectrometry data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1931

Tau phosphorylation and proteolysis: insights and perspectives.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26436840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The dynamic structure of filamentous tau

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26436840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of two VQIXXK motifs for tau fibrillization in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26436840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1931

1 reference

17 October 2017

1 reference