(Q42222741)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

Splicing factor 3b subunit 1

21 March 2020

main subject

1 reference

Splicing factor 3b subunit 6

1 reference

Splicing factor 3b subunit 4

1 reference

PHD finger protein 5A

1 reference

Splicing factor 3b subunit 3

1 reference

Splicing factor 3b subunit 5

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Jennifer Hc Tsai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xiaoling Puyang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Michael Seiler

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Shouyong Peng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Sudeep Prajapati

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Daniel Aird

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Silvia Buonamici

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Benjamin Caleb

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Betty Chan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Laura Corson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Jacob Feala

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Peter Fekkes

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Baudouin Gerard

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Craig Karr

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Manav Korpal

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xiang Liu

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Jason T Lowe

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Yoshiharu Mizui

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

James Palacino

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Eunice Park

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Peter G Smith

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Vanitha Subramanian

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Zhenhua Jeremy Wu

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Jian Zou

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Lihua Yu

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Agustin Chicas

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Markus Warmuth

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Nicholas Larsen

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Ping Zhu

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

25 May 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

15522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

25 May 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5458519

inferred from PubMed Central ID database lookup

cites work

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Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution

26 October 2017

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Structure of a yeast activated spliceosome at 3.5 Å resolution

26 October 2017

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26 October 2017

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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point

26 October 2017

1 reference

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The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia.

26 October 2017

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26 October 2017

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SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

26 October 2017

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26 October 2017

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SF3B1 association with chromatin determines splicing outcomes

26 October 2017

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Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells

26 October 2017

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Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

26 October 2017

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A day in the life of the spliceosome

26 October 2017

1 reference

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Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives

26 October 2017

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26 October 2017

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Automatic protein structure solution from weak X-ray data.

26 October 2017

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Enantioselective syntheses of FR901464 and spliceostatin A: potent inhibitors of spliceosome

26 October 2017

1 reference

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Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

26 October 2017

1 reference

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An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).

26 October 2017

1 reference

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26 October 2017

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Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

26 October 2017

1 reference

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26 October 2017

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Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells

26 October 2017

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26 October 2017

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The spliceosome as a target of novel antitumour drugs

26 October 2017

1 reference

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26 October 2017

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26 October 2017

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Biological validation that SF3b is a target of the antitumor macrolide pladienolide

26 October 2017

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26 October 2017

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Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

26 October 2017

1 reference

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The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

26 October 2017

1 reference

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GC content around splice sites affects splicing through pre-mRNA secondary structures

26 October 2017

1 reference

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A stereoselective synthesis of (+)-herboxidiene/GEX1A.

26 October 2017

1 reference

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Dali server: conservation mapping in 3D

26 October 2017

1 reference

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Features and development of Coot

26 October 2017

1 reference

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Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

26 October 2017

1 reference

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Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif

26 October 2017

1 reference

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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

26 October 2017

1 reference

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Sticky fingers: zinc-fingers as protein-recognition motifs

26 October 2017

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

26 October 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

Structural classification of zinc fingers: survey and summary

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

NAMPT is the cellular target of STF-31-like small-molecule probes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

A phase I, open-label, single-arm, dose-escalation study of E7107, a precursor messenger ribonucleic acid (pre-mRNA) splicesome inhibitor administered intravenously on days 1 and 8 every 21 days to patients with solid tumors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5458519

Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS15522

Identification of SAP155 as the Target of GEX1A (Herboxidiene), an Antitumor Natural Product

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS15522

A blueprint for advancing genetics-based cancer therapy

21 January 2018

1 reference

Crossref

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7 January 2021

inferred from DOI database lookup

Distributions of exons and introns in the human genome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28541300

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS15522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

0 references

release_lcgcewaozzgajntuvbxq4nesry

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lcgcewaozzgajntuvbxq4nesry

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28541300%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

28541300

1 reference