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A day in the life of the spliceosome
scientific article published on February 2014
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scholarly article
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Europe PubMed Central
PMC publication ID
4060434
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
title
A day in the life of the spliceosome
(English)
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Europe PubMed Central
PMC publication ID
4060434
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
main subject
spliceosome
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author
A. Gregory Matera
series ordinal
1
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Europe PubMed Central
PMC publication ID
4060434
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
Zefeng Wang
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2
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Europe PubMed Central
PMC publication ID
4060434
reference URL
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6 March 2020
author name string
A Gregory Matera
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1
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4060434
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30 August 2017
publication date
1 February 2014
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4060434
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6 March 2020
published in
Nature Reviews Molecular Cell Biology
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PMC publication ID
4060434
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6 March 2020
volume
15
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4060434
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retrieved
6 March 2020
issue
2
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Europe PubMed Central
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4060434
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6 March 2020
page(s)
108-121
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6 March 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nrm3742
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Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila
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Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly
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Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I
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PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.
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6 September 2017
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6 September 2017
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6 September 2017
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6 September 2017
Structural insights into RNA splicing
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6 September 2017
Drosophila hnRNP A1 homologs Hrp36/Hrp38 enhance U2-type versus U12-type splicing to regulate alternative splicing of the prospero twintron
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6 September 2017
Coilin is essential for Cajal body organization in Drosophila melanogaster.
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6 September 2017
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs
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6 September 2017
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes
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6 September 2017
Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster
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6 September 2017
Crystal Structure of a Self-Spliced Group II Intron
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retrieved
6 September 2017
Splicing regulation: from a parts list of regulatory elements to an integrated splicing code
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Coevolutionary networks of splicing cis-regulatory elements
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
The long unwinding road of RNA helicases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-2 3'-UTR
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Multiple features contribute to the use of the immunoglobulin M secretion-specific poly(A) signal but are not required for developmental regulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Molecular anatomy of a speckle
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Pumping RNA: nuclear bodybuilding along the RNP pipeline.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
The architecture of pre-mRNAs affects mechanisms of splice-site pairing.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Functional studies on the ATM intronic splicing processing element
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Cross-talk between snurportin1 subdomains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Understanding alternative splicing: towards a cellular code
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Systematic identification and analysis of exonic splicing silencers.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Detection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transfer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
A role for Cajal bodies in the final steps of U2 snRNP biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
The spliceosome: the most complex macromolecular machine in the cell?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Nuclear speckles: a model for nuclear organelles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Pre-mRNA splicing: awash in a sea of proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Nuclear RNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Essential role for the SMN complex in the specificity of snRNP assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
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6 September 2017
Comprehensive proteomic analysis of the human spliceosome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The U1 snRNP protein U1C recognizes the 5' splice site in the absence of base pairing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
RH70, a bidirectional RNA helicase, co-purifies with U1snRNP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Composition and functional characterization of the yeast spliceosomal penta-snRNP.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
RNA-mediated interaction of Cajal bodies and U2 snRNA genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
SMN tudor domain structure and its interaction with the Sm proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Interactions of U2 gene loci and their nuclear transcripts with Cajal (coiled) bodies: evidence for PreU2 within Cajal bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Multiple splicing defects in an intronic false exon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p, share structural and functional similarity with the spinal muscular atrophy-associated proteins SMN and SIP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
CRM1 is an export receptor for leucine-rich nuclear export signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Architectural limits on split genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
A nuclear cap binding protein complex involved in pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Dynamic RNA-RNA interactions in the spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Are snRNPs involved in splicing?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Spliced segments at the 5′ terminus of adenovirus 2 late mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
6 September 2017
Counting on co-transcriptional splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
Co-transcriptional commitment to alternative splice site selection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
RNA length defines RNA export pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
14 September 2017
A new type of mutation causes a splicing defect in ATM.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
hnRNP L and hnRNP A1 induce extended U1 snRNA interactions with an exon to repress spliceosome assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
U1 snRNP-mediated poly(A) site suppression: beneficial and deleterious for mRNA fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
28 September 2017
Ordered and dynamic assembly of single spliceosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
snRNA-specific role of SMN in trypanosome snRNP biogenesis in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Cajal body surveillance of U snRNA export complex assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Identification of novel snRNA-specific Sm proteins that bind selectively to U2 and U4 snRNAs in Trypanosoma brucei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Nuclear import of U snRNPs requires importin beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
Spliced leader RNAs from lower eukaryotes are trans-spliced in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
23 June 2018
CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Size matters in RNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
hnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
RNA secondary structure in mutually exclusive splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Isolation of an active step I spliceosome and composition of its RNP core.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Role of poly (A) tail as an identity element for mRNA nuclear export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
An RNA map predicting Nova-dependent splicing regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Identity elements used in export of mRNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060434
retrieved
31 August 2018
Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
SMN oligomerization defect correlates with spinal muscular atrophy severity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
The integrator complex is required for integrity of Cajal bodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
Both catalytic steps of nuclear pre-mRNA splicing are reversible
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
8. The Spliceosome and Its Metal Ions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
An exonic splicing silencer represses spliceosome assembly after ATP-dependent exon recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRM3742
retrieved
31 March 2020
Identifiers
DOI
10.1038/NRM3742
1 reference
stated in
Europe PubMed Central
PMC publication ID
4060434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
Dimensions Publication ID
1015721282
0 references
PMC publication ID
4060434
1 reference
stated in
Europe PubMed Central
PMC publication ID
4060434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PubMed publication ID
24452469
1 reference
stated in
Europe PubMed Central
PMC publication ID
4060434
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24452469%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
ResearchGate publication ID
259877421
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