(Q38406831)

English

Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives

scientific article published on 30 December 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives (English)

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

author name string

Chandraiah Lagisetti

1

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Maria V Yermolina

2

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Lalit Kumar Sharma

3

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Gustavo Palacios

4

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Brett J Prigaro

5

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Thomas R Webb

6

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

30 December 2013

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

ACS Chemical Biology

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

643-648

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Enantioselective syntheses of FR901464 and spliceostatin A: potent inhibitors of spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Alternative RNA splicing and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Targeting RNA splicing for disease therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

The spliceosome as a target of novel antitumour drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Enantioselective total synthesis of pladienolide B: a potent spliceosome inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

The development and application of small molecule modulators of SF3b as therapeutic agents for cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Design, synthesis and initial biological evaluation of a novel pladienolide analog scaffold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

RNA splicing: disease and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

A stereoselective synthesis of (+)-herboxidiene/GEX1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Synthetic mRNA splicing modulator compounds with in vivo antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Total synthesis of herboxidiene/GEX 1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Mechanisms of alternative pre-messenger RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

6 September 2017

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

14 September 2017

Antitumor compounds based on a natural product consensus pharmacophore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

14 September 2017

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

14 September 2017

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

14 September 2017

GEX1 compounds, novel antitumor antibiotics related to herboxidiene, produced by Streptomyces sp. II. The effects on cell cycle progression and gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

14 September 2017

Stabilized cyclopropane analogs of the splicing inhibitor FD-895

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

23 June 2018

Structure of FD-895 revealed through total synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

23 June 2018

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

23 June 2018

New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

23 June 2018

Large-scale synthesis of all stereoisomers of a 2,3-unsaturated C-glycoside scaffold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

Electrophile-induced ether transfer: stereoselective synthesis of 2,6-disubstituted-3,4-dihydropyrans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

GEX1 compounds, novel antitumor antibiotics related to herboxidiene, produced by Streptomyces sp. I. Taxonomy, production, isolation, physicochemical properties and biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

31 August 2018

Identification of SAP155 as the Target of GEX1A (Herboxidiene), an Antitumor Natural Product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3962696

3 December 2018

Stereospecific synthesis of cryptophycin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantioselective synthesis of pladienolide B and truncated analogues as new anticancer agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of the potent antitumor macrolides pladienolide B and D

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FR901464: total synthesis, proof of structure, and evaluation of synthetic analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantioselective construction of cis-2,6-disubstituted dihydropyrans: total synthesis of (-)-centrolobine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of GEX1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of splicing factor 3b inhibitors in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of (+)-herboxidiene from two chiral lactate-derived ketones

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/24377313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. I. Taxonomy, Production, Isolation, Physicochemical Properties and Biological Activities.

1 reference

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.855

12 April 2024

Identifiers

10.1021/CB400695J

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

ResearchGate publication ID

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