(Q42281690)

19 October 2017

title

PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice (English)

1 reference

19 October 2017

0 references

1 reference

8

1 reference

19 October 2017

10

1 reference

19 October 2017

9

M Croyle

1 reference

19 October 2017

E Leggiero

1

1 reference

19 October 2017

D Astone

2

1 reference

19 October 2017

V Cerullo

3

1 reference

19 October 2017

B Lombardo

4

1 reference

19 October 2017

C Mazzaccara

5

1 reference

19 October 2017

G Labruna

6

1 reference

19 October 2017

L Sacchetti

7

1 reference

19 October 2017

publication date

25 July 2013

1 reference

19 October 2017

1 reference

19 October 2017

volume

20

1 reference

19 October 2017

issue

12

1 reference

19 October 2017

page(s)

1124-1130

1 reference

ABC transporters, atherosclerosis and inflammation

19 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Guidelines for the diagnosis and management of heterozygous familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Identification of a novel human cellular HDL biosynthesis defect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

ATP-Binding cassette cholesterol transporters and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

New insights into the regulation of HDL metabolism and reverse cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Is it time for a cardiovascular primary prevention trial in the elderly?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

HDL cholesterol and protective factors in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Gene therapy to improve high-density lipoprotein metabolism and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Sustained expression of human apo A-I following adenoviral gene transfer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Long-Term Stable Expression of Human Apolipoprotein A-I Mediated by Helper-Dependent Adenovirus Gene Transfer Inhibits Atherosclerosis Progression and Remodels Atherosclerotic Plaques in a Mouse Model of Familial Hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Reversal of metabolic and neurological symptoms of phenylketonuric mice treated with a PAH containing helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

The innate immune response to adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Species differences in the pharmacology and toxicology of PEGylated helper-dependent adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Blood clearance rates of adenovirus type 5 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Modification of adenoviral vectors with polyethylene glycol modulates in vivo tissue tropism and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Effects of shielding adenoviral vectors with polyethylene glycol on vector-specific and vaccine-mediated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Short-term rescue of neonatal lethality in a mouse model of propionic acidemia by gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Comparison of adenoviruses as oncolytics and cancer vaccines in an immunocompetent B cell lymphoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Immune recognition of gene transfer vectors: focus on adenovirus as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Balloon catheter delivery of helper-dependent adenoviral vector results in sustained, therapeutic hFIX expression in rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Phenotypic correction of ornithine transcarbamylase deficiency using low dose helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Generation of helper-dependent adenoviral vectors by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Improved system for helper-dependent adenoviral vector production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Differential inflammatory activation of IL-6 (-/-) astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

Apolipoprotein A-I mimetic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

inferred from DOI database lookup

7 January 2021

based on heuristic

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

inferred from DOI database lookup

7 January 2021

based on heuristic

Helper-dependent adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2013.38

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GT.2013.38

1 reference

Dimensions Publication ID

19 October 2017

1009690978

0 references

1 reference