(Q42315227)

25 October 2017

Kras is Required for Adult Hematopoiesis (English)

1 reference

25 October 2017

0 references

Xiaona You

6

0 references

author name string

Alisa Damnernsawad

1

1 reference

25 October 2017

Guangyao Kong

2

1 reference

25 October 2017

Zhi Wen

3

1 reference

25 October 2017

Yangang Liu

4

1 reference

25 October 2017

Adhithi Rajagopalan

5

1 reference

25 October 2017

Jinyong Wang

7

1 reference

25 October 2017

Yun Zhou

8

1 reference

25 October 2017

Erik A Ranheim

9

1 reference

25 October 2017

Hongbo R Luo

10

1 reference

25 October 2017

Qiang Chang

11

1 reference

25 October 2017

Jing Zhang

12

1 reference

25 October 2017

12 March 2016

1 reference

25 October 2017

1 reference

25 October 2017

34

1 reference

25 October 2017

7

1 reference

25 October 2017

1859-1871

1 reference

Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Kras Is Critical for B Cell Lymphopoiesis

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Targeting oncogenic Ras signaling in hematologic malignancies

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

The expression of the glucocorticoid receptor in human erythroblasts is uniquely regulated by KIT ligand: implications for stress erythropoiesis.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Endothelial and perivascular cells maintain haematopoietic stem cells

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Of lineage and legacy: the development of mammalian hematopoietic stem cells

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

A highly efficient recombineering-based method for generating conditional knockout mutations

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

25 October 2017

Kit signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

The murine N-ras gene is not essential for growth and development

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Inducible gene targeting in mice

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.

25 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Kit regulates maintenance of quiescent hematopoietic stem cells.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Endogenous K-ras signaling in erythroid differentiation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358545

Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FSTEM.2355

K-ras is essential for the development of the mouse embryo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26972179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mice deficient for N-ras: impaired antiviral immune response and T-cell function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26972179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26972179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/STEM.2355

1 reference

25 October 2017

1 reference

25 October 2017

PubMed publication ID

26972179

1 reference