(Q42447288)

31 October 2017

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration (English)

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31 October 2017

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17

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31 October 2017

Christine D Pozniak

1

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31 October 2017

Arundhati Sengupta Ghosh

2

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31 October 2017

Alvin Gogineni

3

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31 October 2017

Jesse E Hanson

4

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31 October 2017

Seung-Hye Lee

5

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31 October 2017

Jessica L Larson

6

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31 October 2017

Hilda Solanoy

7

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31 October 2017

Daisy Bustos

8

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31 October 2017

Hong Li

9

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31 October 2017

Hai Ngu

10

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31 October 2017

Adrian M Jubb

11

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31 October 2017

Gai Ayalon

12

1 reference

31 October 2017

Jiansheng Wu

13

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31 October 2017

Kimberly Scearce-Levie

14

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31 October 2017

Qiang Zhou

15

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31 October 2017

Robby M Weimer

16

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31 October 2017

Joseph W Lewcock

18

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31 October 2017

language of work or name

English

0 references

publication date

28 October 2013

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Journal of Experimental Medicine

31 October 2017

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31 October 2017

210

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31 October 2017

12

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31 October 2017

2553-2567

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describes a project that uses

31 October 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3832926

inferred from PubMed Central ID database lookup

cites work

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

1 reference

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DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury.

28 May 2018

1 reference

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Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration

28 May 2018

1 reference

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The postsynaptic organization of synapses

28 May 2018

1 reference

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DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

28 May 2018

1 reference

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Hippocampal c-Jun-N-Terminal Kinases Serve as Negative Regulators of Associative Learning

28 May 2018

1 reference

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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

28 May 2018

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Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

28 May 2018

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Glutamate receptors, neurotoxicity and neurodegeneration

28 May 2018

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c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges.

28 May 2018

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Sunday driver interacts with two distinct classes of axonal organelles.

28 May 2018

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A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration

28 May 2018

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An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan

28 May 2018

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A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping

28 May 2018

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Chemoconvulsant model of chronic spontaneous seizures

28 May 2018

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Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.

28 May 2018

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The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists

28 May 2018

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Context-specific inhibition of JNKs: overcoming the dilemma of protection and damage

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Rap2-JNK removes synaptic AMPA receptors during depotentiation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Development of long-term dendritic spine stability in diverse regions of cerebral cortex

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Sunday Driver links axonal transport to damage signaling

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Transient and persistent dendritic spines in the neocortex in vivo

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Identification and verification of novel rodent postsynaptic density proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Molecular constituents of the postsynaptic density fraction revealed by proteomic analysis using multidimensional liquid chromatography-tandem mass spectrometry.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

A critical role of neural-specific JNK3 for ischemic apoptosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Contactin supports synaptic plasticity associated with hippocampal long-term depression but not potentiation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Identification of proteins in the postsynaptic density fraction by mass spectrometry

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Apoptosis and necrosis in cerebrovascular disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Postsynaptic density antigens: preparation and characterization of an antiserum against postsynaptic densities

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Glutamate neurotoxicity in cortical cell culture is calcium dependent

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

c-Jun phosphorylation in Alzheimer disease

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832926

Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers

16 August 2018

1 reference

12 December 2020

Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins

1 reference

12 December 2020

Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice

1 reference

12 December 2020

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase

1 reference

12 December 2020

Efficient gene transfer into the embryonic mouse brain using in vivo electroporation

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20122832

1 reference

release_oyouacgzfzar5icyny2amdttvy

31 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oyouacgzfzar5icyny2amdttvy

24 November 2022

mapped directly with Wikidata item

1 reference

31 October 2017

PubMed publication ID

24166713

1 reference