(Q42497012)

1 November 2017

title

Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia (English)

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1 November 2017

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5

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1 November 2017

Yohannes Tesfaigzi

6

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author name string

Joseph Pierce

1

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1 November 2017

Jules Rir-Sima-Ah

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1 November 2017

Isaac Estrada

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1 November 2017

Julie Wilder

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1 November 2017

publication date

16 June 2006

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American Journal of Physiology - Lung Cellular and Molecular Physiology

1 November 2017

published in

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1 November 2017

volume

291

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1 November 2017

issue

5

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1 November 2017

page(s)

L862-70

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Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.

1 November 2017

cites work

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Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

21 January 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells.

21 January 2018

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Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

21 January 2018

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Airway remodeling in asthma

21 January 2018

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Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

21 January 2018

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Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

21 January 2018

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Mucin is produced by clara cells in the proximal airways of antigen-challenged mice

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Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation

21 January 2018

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

21 January 2018

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BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

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Effect of acute and chronic antigen inhalation on airway morphology and responsiveness in actively sensitized rats

21 January 2018

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Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

21 January 2018

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Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL.

21 January 2018

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Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

21 January 2018

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

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21 January 2018

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The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

21 January 2018

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Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation

21 January 2018

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Pathogenesis of mucous cell metaplasia in a murine asthma model

21 January 2018

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Reactive oxygen species limit neutrophil life span by activating death receptor signaling

21 January 2018

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Chronic inhaled ovalbumin exposure induces antigen-dependent but not antigen-specific inhalational tolerance in a murine model of allergic airway disease

21 January 2018

1 reference

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Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization

21 January 2018

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IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.

21 January 2018

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Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity

21 January 2018

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

21 January 2018

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Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia.

21 January 2018

1 reference

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DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS.

21 January 2018

1 reference

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Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways

21 January 2018

1 reference

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Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family

21 January 2018

1 reference

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Maintenance of differentiated murine Clara cells in microdissected airway cultures

21 January 2018

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Transfer of allergic airway responses with antigen-primed CD4+ but not CD8+ T cells in brown Norway rats

21 January 2018

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Interleukin-13: central mediator of allergic asthma

21 January 2018

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Shifts in lung lymphocyte profiles correlate with the sequential development of acute allergic and chronic tolerant stages in a murine asthma model

21 January 2018

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Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro.

21 January 2018

1 reference

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00516.2005

10.1152/AJPLUNG.00516.2005

21 January 2018

Identifiers

DOI

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1 November 2017

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