(Q42509342)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

4

1 reference

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7 February 2020

author name string

F Bai

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

M D Smith

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

H L Chan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

9 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

2715-2725

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer

7 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

p63 correlates with both BRCA1 and cytokeratin 5 in invasive breast carcinomas: further evidence for the pathogenesis of the basal phenotype of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 functions as a breast stem cell regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 regulates human mammary stem/progenitor cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

p18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Deletions of CDKN2C in multiple myeloma: biological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Signatures of mutation and selection in the cancer genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Generation of a functional mammary gland from a single stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

E-cadherin null mutant embryos fail to form a trophectoderm epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Epithelial progenitors in the normal human mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Brca1 regulates in vitro differentiation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The role of BRCA1 in transcriptional regulation and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 regulation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Preclinical mouse models for BRCA1-associated breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

The molecular pathology of hereditary breast cancer: genetic testing and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Mixed epithelial/mesenchymal metaplastic carcinoma (carcinosarcoma) of the breast in BRCA1 carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Distinct stem cells contribute to mammary gland development and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

BRCA1--conductor of the breast stem cell orchestra: the role of BRCA1 in mammary gland development and identification of cell of origin of BRCA1 mutant breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

Purification and unique properties of mammary epithelial stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.293

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 February 2020

1020031510

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22777348%20AND%20SRC:MED&resulttype=core&format=json