(Q42744479)

6 November 2017

title

Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes (English)

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6 November 2017

2

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6 November 2017

4

Tamara Vanhaecke

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6 November 2017

5

Vera Rogiers

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6 November 2017

Joanna Edyta Fraczek

1

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6 November 2017

Dirk Tourwé

series ordinal

3

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6 November 2017

language of work or name

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29 March 2011

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Investigational New Drugs

6 November 2017

published in

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6 November 2017

volume

30

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6 November 2017

issue

4

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6 November 2017

page(s)

1715-1724

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https://scigraph.springernature.com/pub.10.1007/s10637-011-9659-8

6 November 2017

exact match

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cites work

Epigenetics, DNA methylation, and chromatin modifying drugs

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

DNA Methylation and Epigenetic Inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Therapeutic implications of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

DNA methylation and demethylation as targets for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Epigenetic gene silencing in cancer: the DNA hypermethylome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2'-deoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

HDAC inhibitors: clinical update and mechanism-based potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Clinical studies of histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Histone deacetylase inhibitors as anti-neoplastic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Mammalian cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

In vitro basis for treatment with hypomethylating agents and histone deacetylase inhibitors: can epigenetic changes be used to monitor treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Epigenetics in human disease and prospects for epigenetic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Epigenetics and cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Amide Analogues of Trichostatin A as Inhibitors of Histone Deacetylase and Inducers of Terminal Cell Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9659-8

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

21 January 2018

1 reference

12 December 2020

Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome

1 reference

12 December 2020

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

1 reference

12 December 2020

Isolation of rat hepatocytes.

1 reference

12 December 2020

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

1 reference

12 December 2020

Decitabine in myelodysplastic syndromes: viewpoints

1 reference

12 December 2020

Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer

1 reference

12 December 2020

Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes

1 reference

12 December 2020

DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.

1 reference

12 December 2020

Proliferation of epidermal growth factor-stimulated hepatocytes in a hormonally defined serum-free medium.

1 reference

12 December 2020

Influence of culture time on the expression of drug-metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2

1 reference

12 December 2020

10.1007/S10637-011-9659-8

Identifiers

DOI

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Dimensions Publication ID

6 November 2017

1051895965

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