(Q42791128)

English

Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells

scientific article published on July 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells (English)

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Boris Krasnikov

3

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

author name string

Lei Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Arthur J L Cooper

2

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Hui Xu

4

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Parvesh Bubber

5

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

John T Pinto

6

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Gary E Gibson

7

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Marie H Hanigan

8

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

language of work or name

0 references

publication date

1 July 2006

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

45

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

29

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

8959-8971

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Cisplatin nephrotoxicity: molecular mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Cysteine S-conjugate beta-lyases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

A novel protocol for the subcellular fractionation of C3A hepatoma cells using sucrose density gradient centrifugation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Cisplatin: mode of cytotoxic action and molecular basis of resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Cisplatin and platinum drugs at the molecular level. (Review)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Cisplatin-induced encephalopathy and seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Tissue expression and translational control of rat kynurenine aminotransferase/glutamine transaminase K mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Curing metastatic cancer: lessons from testicular germ-cell tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Role of CysteineS-Conjugate β-Lyase in the Metabolism of Cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Metabolism of Cisplatin to a nephrotoxin in proximal tubule cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Divergent Hsc70 binding properties of mitochondrial and cytosolic aspartate aminotransferase. Implications for their segregation to different cellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mechanisms of cysteine S-conjugate beta-lyases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Protein folding in a cell-free translation system. The fate of the precursor to mitochondrial aspartate aminotransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Isolation from rat kidney of a cytosolic high molecular weight cysteine-S-conjugate beta-lyase with activity toward leukotriene E4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mitochondrial bioactivation of cysteine S-conjugates and 4-thiaalkanoates: Implications for mitochondrial dysfunction and mitochondrial diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Use of beta-methylene-D,L-aspartate to assess the role of aspartate aminotransferase in cerebral oxidative metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

The antitumor agent cis-Pt(NH 3 ) 2 Cl 2 : distribution studies and dose calculations for 193m Pt and 195m Pt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Separate enzymatic microassays for aspartate aminotransferase isoenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

27 May 2018

Analysis of cytotoxicities of platinum compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Effects of cisplatin on mitochondrial function in Jurkat cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of Cisplatin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Co-purification of mitochondrial HSP70 and mature protein disulfide isomerase with a functional rat kidney high-M(r) cysteine S-conjugate beta-lyase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Developmental modulation of cysteine conjugate beta-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Dependence of the folding and import of the precursor to mitochondrial aspartate aminotransferase on the nature of the cell-free translation system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Glutamine transaminase K is not a major cysteine S-conjugate beta-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4133109

16 August 2018

Glutathione-dependent bioactivation of haloalkenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and properties of a liver mitochondrial precursor protein to aspartate aminotransferase expressed in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cisplatin-induced nephrotoxicity in rats by buthionine sulfoximine, a glutathione synthesis inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na-dependent transport of S-(1,2-dichlorovinyl)-L-cysteine by renal brush-border membrane vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal catabolism of glutathione. Characterization of a particulate rat renal dipeptidase that catalyzes the hydrolysis of cysteinylglycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione-degrading enzymes of microvillus membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of γ-glutamyltranspeptidase and β-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Features of microsomal and cytosolic glutathione conjugation of hexachlorobutadiene in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin metabolites in plasma, a study of their pharmacokinetics and importance in the nephrotoxic and antitumour activity of cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insight into the conformation of protein folding intermediate(s) trapped by GroEL

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of glutamine transaminase K/cysteine conjugate beta-lyase from rat renal cytosol based on hydrophobic interaction HPLC and gel permeation FPLC

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting 6-thioguanine to the kidney with S-(guanin-6-yl)-L-cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16846239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI060027G

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

ResearchGate publication ID

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