(Q42803099)

7 November 2017

Tpl-2 kinase downregulates the activity of p53 and enhances signaling pathways leading to activation of activator protein 1 induced by EGF. (English)

1 reference

7 November 2017

Prem Khanal

1

1 reference

7 November 2017

Kwang-Youl Lee

2

1 reference

7 November 2017

Keon-Wook Kang

3

1 reference

7 November 2017

Bong Seok Kang

4

1 reference

7 November 2017

Hong Seok Choi

5

1 reference

7 November 2017

language of work or name

English

0 references

publication date

12 February 2009

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7 November 2017

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7 November 2017

30

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7 November 2017

4

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7 November 2017

682-689

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Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.

7 November 2017

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Expression of the Tpl2/Cot oncogene in human T-cell neoplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Mutational activation of the MAP3K8 protooncogene in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Cot kinase activates tumor necrosis factor-alpha gene expression in a cyclosporin A-resistant manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Post-translational modification of p53 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Transcriptional activation of the human epidermal growth factor receptor promoter by human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Wild-type but not mutant p53 activates the hepatocyte growth factor/scatter factor promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Introduction: p53--the first twenty years

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

AP-1: a double-edged sword in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

The regulation of transcription by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP040

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGP040

1 reference

7 November 2017

1 reference