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Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.
scientific article published on December 2002
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
title
Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
main subject
apoptotic process
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Vaccinia virus
object named as
vaccinia virus
1 reference
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author
Maria A Garcia
series ordinal
1
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Jesus Gil
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3
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Mariano Esteban
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5
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Mariano Esteban
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
author name string
Susana Guerra
series ordinal
2
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Victoria Jimenez
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
language of work or name
English
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publication date
1 December 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
volume
21
1 reference
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
issue
55
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
page(s)
8379-8387
1 reference
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Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
cites work
Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity
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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
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The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties
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Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model
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Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.
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Host-range restriction of vaccinia virus E3L-specific deletion mutants
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Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.
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A study of the interferon antiviral mechanism: apoptosis activation by the 2-5A system
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7 January 2021
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The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
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JNK2 and IKKbeta are required for activating the innate response to viral infection
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7 January 2021
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The double-stranded RNA-dependent protein kinase PKR: structure and function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
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7 January 2021
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Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53
1 reference
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Crossref
reference URL
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7 January 2021
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The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro
1 reference
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Crossref
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7 January 2021
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The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
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7 January 2021
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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
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7 January 2021
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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
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Activation of the IFN-inducible enzyme RNase L causes apoptosis of animal cells.
1 reference
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A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling
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Crossref
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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
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Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection
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The IRF-3 transcription factor mediates Sendai virus-induced apoptosis
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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.
1 reference
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Crossref
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Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells
1 reference
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Activation of interferon regulatory factor 3 in response to DNA-damaging agents
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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase
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The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus
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The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
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Regulated expression of the interferon-induced protein kinase p68 (PKR) by vaccinia virus recombinants inhibits the replication of vesicular stomatitis virus but not that of poliovirus
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Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor
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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
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Identification by mass spectroscopy of three major early proteins associated with virosomes in vaccinia virus-infected cells
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1 reference
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The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties
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Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.
1 reference
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Crossref
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IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein
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Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase
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Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity
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The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death?
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Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK)
1 reference
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Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase
1 reference
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Crossref
reference URL
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PKR; a sentinel kinase for cellular stress
1 reference
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Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.
1 reference
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Crossref
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7 January 2021
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Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
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Crossref
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7 January 2021
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inferred from DOI database lookup
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
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7 January 2021
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inferred from DOI database lookup
Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1206036
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1206036
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Dimensions Publication ID
1037960225
0 references
PubMed publication ID
12466958
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12466958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12466958%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
ResearchGate publication ID
6989775
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