(Q42815050)

7 November 2017

Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases (English)

1 reference

7 November 2017

Cercina Onesto

1

1 reference

7 November 2017

Adam Shutes

2

1 reference

7 November 2017

Virginie Picard

3

1 reference

7 November 2017

Fabien Schweighoffer

4

1 reference

7 November 2017

Channing J Der

5

1 reference

7 November 2017

language of work or name

English

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publication date

1 January 2008

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7 November 2017

Methods in Enzymology

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7 November 2017

439

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7 November 2017

111-129

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Lipid posttranslational modifications. Farnesyl transferase inhibitors

7 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

The role of Rho GTPases in disease development

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Biological assays for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

VAV1: a new target in pancreatic cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rho GTPases are over-expressed in human tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Expression of Rac3 in human brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Molecular basis for Rho GTPase signaling specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

The mechanism of Ras GTPase activation by neurofibromin.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rac is required for v-Abl tyrosine kinase to activate mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Role of magnesium in nucleotide exchange on the small G protein rac investigated using novel fluorescent Guanine nucleotide analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Analyses of transforming activity of Rho family activators

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Structural and biophysical insights into the role of the insert region in Rac1 function

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2900409-0

7 January 2021

10.1016/S0076-6879(07)00409-0

Identifiers

DOI

1 reference

7 November 2017

1 reference