(Q42818782)

English

Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias

scientific article published on 11 February 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Neal G. Copeland

5

object named as

Neal G Copeland

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Nancy A. Jenkins

4

object named as

Nancy A Jenkins

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

author name string

Karen L Himmel

1

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Feng Bi

2

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Haifa Shen

3

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Yi Zheng

6

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

David A Largaespada

7

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

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publication date

11 February 2002

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

7 November 2017

277

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

16

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Europe PubMed Central

PubMed publication ID

7 November 2017

13463-13472

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies

1 reference

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Genetic profile of insertion mutations in mouse leukemias and lymphomas

1 reference

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The Dbl family of oncogenes

1 reference

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Regulation of cell function by Rho family GTPases

1 reference

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Rho GTPases and their effector proteins

1 reference

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Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development.

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Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

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A role for Rho in Ras transformation

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

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Molecular biology of chronic myeloid leukemia

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Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

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A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

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Guanine nucleotide exchange catalyzed by dbl oncogene product

1 reference

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Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

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A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

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The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes

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Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach

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Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames

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Vav2 is an activator of Cdc42, Rac1, and RhoA

1 reference

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21 January 2018

Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA

1 reference

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21 January 2018

Evi-2, a common integration site involved in murine myeloid leukemogenesis

1 reference

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21 January 2018

Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia

1 reference

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21 January 2018

Guanine nucleotide exchange factors: activators of Ras superfamily proteins

1 reference

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21 January 2018

The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110981200

21 January 2018

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110981200

21 January 2018

Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42

1 reference

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21 January 2018

Guanine nucleotide exchange factors for the Rho GTPases: a role in human disease?

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21 January 2018

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

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21 January 2018

Multiple roles for Cdc42 in cell regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110981200

21 January 2018

The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation

1 reference

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21 January 2018

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

1 reference

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21 January 2018

The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis

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21 January 2018

Activated PAK4 regulates cell adhesion and anchorage-independent growth

1 reference

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21 January 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

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21 January 2018

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

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21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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21 January 2018

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro

1 reference

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21 January 2018

Cdc42 is a substrate for caspases and influences Fas-induced apoptosis

1 reference

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Sensitivity to Fas-mediated apoptosis is null or weak in B-cell non-Hodgkin's lymphomas and is moderately increased by CD40 ligation

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Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development

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The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

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Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

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The Sequence of the Human Genome

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Initial sequencing and analysis of the human genome

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Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

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Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos

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Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

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The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

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Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

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21 January 2018

Identifiers

10.1074/JBC.M110981200

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

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