(Q42873146)

English

Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation

scientific article published on July 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation (English)

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

phosphorylation

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

object named as

Irene Chiolo

1

0 references

Giordano Liberi

object named as

Giordano Liberi

6

0 references

object named as

Marco Foiani

5

0 references

author name string

Walter Carotenuto

2

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Giulio Maffioletti

3

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

language of work or name

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publication date

1 July 2005

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Europe PubMed Central

PMC publication ID

9 November 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

9 November 2017

25

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

13

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

5738-5751

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase

1 reference

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DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

1 reference

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1 reference

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1 reference

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Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.

1 reference

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1 reference

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Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

1 reference

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27 May 2018

Mre11 assembles linear DNA fragments into DNA damage signaling complexes

1 reference

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Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.

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Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

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1 reference

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Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model

1 reference

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27 May 2018

Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

1 reference

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Targets of the cyclin-dependent kinase Cdk1

1 reference

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Requirement of the MRN complex for ATM activation by DNA damage

1 reference

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Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA Ends

1 reference

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The MRN complex: coordinating and mediating the response to broken chromosomes

1 reference

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RecQ helicases: multiple roles in genome maintenance.

1 reference

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27 May 2018

Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

1 reference

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27 May 2018

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

1 reference

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27 May 2018

DNA helicase Srs2 disrupts the Rad51 presynaptic filament

1 reference

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A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

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RecQ helicases: caretakers of the genome

1 reference

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MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

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DNA structure dependent checkpoints as regulators of DNA repair

1 reference

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Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication

1 reference

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Toward maintaining the genome: DNA damage and replication checkpoints

1 reference

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Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.

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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

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1 reference

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Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III

1 reference

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1 reference

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Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

1 reference

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Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

1 reference

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A unified view of the DNA-damage checkpoint

1 reference

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27 May 2018

Two checkpoint complexes are independently recruited to sites of DNA damage in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

The yeast Xrs2 complex functions in S phase checkpoint regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

1 reference

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Rad52 forms DNA repair and recombination centers during S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

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Participation of recombination proteins in rescue of arrested replication forks in UV-irradiated Escherichia coli need not involve recombination

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Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Regulation and localization of the Bloom syndrome protein in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

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The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

ATM and ATR: networking cellular responses to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

DNA damage-dependent nuclear dynamics of the Mre11 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Interaction between yeast sgs1 helicase and DNA topoisomerase III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

The Bloom's syndrome gene product promotes branch migration of holliday junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex

1 reference

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1 reference

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27 May 2018

Bipartite structure of the SGS1 DNA helicase in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Initiation of genetic recombination and recombination-dependent replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci

1 reference

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Substrate specificities and identification of putative substrates of ATM kinase family members

1 reference

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27 May 2018

Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

27 May 2018

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

1 reference

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Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

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27 May 2018

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase

1 reference

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27 May 2018

Complex formation and functional versatility of Mre11 of budding yeast in recombination

1 reference

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27 May 2018

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

1 reference

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27 May 2018

Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription

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27 May 2018

From DNA damage to cell cycle arrest and suicide: a budding yeast perspective

1 reference

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27 May 2018

Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase.

1 reference

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27 May 2018

Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae

1 reference

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27 May 2018

Correlation of two-hybrid affinity data with in vitro measurements

1 reference

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27 May 2018

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1 reference

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27 May 2018

RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene

1 reference

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27 May 2018

Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

1 reference

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27 May 2018

The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene

1 reference

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27 May 2018

DNA breaks promote genomic instability by impeding proper chromosome segregation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

16 August 2018

Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein

1 reference

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DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray

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Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

16 August 2018

DNA replication-dependent nuclear dynamics of the Mre11 complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

16 August 2018

Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase

1 reference

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16 August 2018

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

1 reference

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Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1156977

16 August 2018

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular response to DNA double-strand breaks: defining the sensors and mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of yeast SGS1 and SRS2 genes for replication and transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S-phase cyclins are required for a stable arrest at metaphase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SGS1 is required for telomere elongation in the absence of telomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc2 Phosphorylation of Crb2 Is Required for Reestablishing Cell Cycle Progression after the Damage Checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome Fragmentation after Induction of a Double-Strand Break Is an Active Process Prevented by the RMX Repair Complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of the Saccharomyces cerevisiae Sgs1 helicase defines an essential function for the Sgs1-Top3 complex in the absence of SRS2 or TOP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process

1 reference

https://pubmed.ncbi.nlm.nih.gov/15964827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.25.13.5738-5751.2005

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

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