(Q42939817)

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The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication.

scientific article published on 5 December 2011

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18 January 2020

The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication (English)

1 reference

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18 January 2020

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18 January 2020

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Sarah K Van Cor-Hosmer

1

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18 January 2020

Waaqo Daddacha

2

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18 January 2020

Z Kelly

3

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18 January 2020

Edward M Kennedy

5

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18 January 2020

Baek Kim

6

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18 January 2020

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5 December 2011

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18 January 2020

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18 January 2020

422

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18 January 2020

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18 January 2020

393-401

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18 January 2020

Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages

1 reference

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Compensatory role of human immunodeficiency virus central polypurine tract sequence in kinetically disrupted reverse transcription

1 reference

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1 reference

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Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate

1 reference

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Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.

1 reference

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Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage

1 reference

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The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases

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Mechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptases

1 reference

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27 May 2018

Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114.

1 reference

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27 May 2018

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

1 reference

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27 May 2018

Glioma-specific and cell cycle-regulated herpes simplex virus type 1 amplicon viral vector.

1 reference

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27 May 2018

A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis

1 reference

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27 May 2018

Human immunodeficiency virus reverse transcriptase and protease sequence database

1 reference

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Adeno-associated virus vectors for gene transfer to the brain.

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Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

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27 May 2018

Role of murine leukemia virus reverse transcriptase deoxyribonucleoside triphosphate-binding site in retroviral replication and in vivo fidelity.

1 reference

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27 May 2018

Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selection

1 reference

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27 May 2018

Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase.

1 reference

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In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues

1 reference

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27 May 2018

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

1 reference

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27 May 2018

Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase

1 reference

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27 May 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

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27 May 2018

Genetic selection in Escherichia coli for active human immunodeficiency virus reverse transcriptase mutants

1 reference

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27 May 2018

Choosing the right sugar: how polymerases select a nucleotide substrate

1 reference

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27 May 2018

Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection

1 reference

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Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis

1 reference

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VMD: visual molecular dynamics

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1 reference

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1 reference

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Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes

1 reference

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Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase

1 reference

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A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication

1 reference

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Presence of M184I/V in minor HIV-1 populations of patients with lamivudine and/or didanosine treatment failure

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1 reference

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1 reference

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16 August 2018

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1 reference

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1 reference

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Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity

1 reference

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1 reference

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16 August 2018

Identifiers

10.1016/J.VIROL.2011.11.004

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18 January 2020

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18 January 2020

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18 January 2020

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