(Q42946637)

11 November 2017

title

Radiosynthesis and in vivo evaluation of [(11)C]MC80 for P-glycoprotein imaging (English)

1 reference

11 November 2017

Radiosynthesis and in vivo evaluation of [11C]MC80 for P-glycoprotein imaging (English)

1 reference

https://api.crossref.org/works/10.1016/J.BMC.2010.06.097

16 June 2024

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Sylvie De Bruyne

1

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11 November 2017

Leonie Wyffels

2

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11 November 2017

Lieselotte Moerman

3

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11 November 2017

Johan Sambre

4

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11 November 2017

Francesco Berardi

6

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11 November 2017

Roberto Perrone

7

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11 November 2017

Filip De Vos

8

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11 November 2017

Nicola A. Colabufo

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20685124

16 June 2024

language of work or name

English

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publication date

4 July 2010

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full work available at URL

11 November 2017

https://api.elsevier.com/content/article/PII:S0968089610006255?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BMC.2010.06.097

https://api.elsevier.com/content/article/PII:S0968089610006255?httpAccept=text/plain

16 June 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMC.2010.06.097

Bioorganic & Medicinal Chemistry

16 June 2024

published in

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11 November 2017

volume

18

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11 November 2017

issue

17

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11 November 2017

page(s)

6489-6495

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

11 November 2017

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P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs

16 June 2024

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Several major antiepileptic drugs are substrates for human P-glycoprotein

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The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

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Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo

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Potential role of drug transporters in the pathogenesis of medically intractable epilepsy

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P-glycoprotein polymorphism in hypo- and hyper-thyroidism patients

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Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

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Altered P-glycoprotein expression in AIDS patients with HIV encephalitis

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beta-Amyloid efflux mediated by p-glycoprotein

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Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

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Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

16 June 2024

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In vivo evaluation of P-glycoprotein function at the blood-brain barrier in nonhuman primates using [11C]verapamil

16 June 2024

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Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function

16 June 2024

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11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux

16 June 2024

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Human brain imaging and radiation dosimetry of 11C-N-desmethyl-loperamide, a PET radiotracer to measure the function of P-glycoprotein

16 June 2024

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99Tcm-sestamibi as an agent for imaging P-glycoprotein-mediated multi-drug resistance: in vitro and in vivo studies in a rat breast tumour cell line and its doxorubicin-resistant variant.

16 June 2024

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4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators

16 June 2024

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Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents

16 June 2024

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An admonition when measuring the lipophilicity of radiotracers using counting techniques

16 June 2024

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P-Glycoprotein, a gatekeeper in the blood-brain barrier

16 June 2024

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The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

16 June 2024

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16 June 2024

Identifiers

1 reference

11 November 2017

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