(Q43027152)

12 November 2017

title

PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study (English)

1 reference

12 November 2017

1 reference

9

1 reference

12 November 2017

12

Jorge S Reis-Filho

1 reference

12 November 2017

Spiros Linardopoulos

10

0 references

Rachael Natrajan

object named as

Rachael Natrajan

2

0 references

Alan Ashworth

11

object named as

Alan Ashworth

1 reference

12 November 2017

1

Maryou B Lambros

1 reference

12 November 2017

3

Felipe C Geyer

1 reference

12 November 2017

5

Konstantin J Dedes

1 reference

12 November 2017

7

Magali Lacroix-Triki

1 reference

12 November 2017

Maria A Lopez-Garcia

4

1 reference

12 November 2017

Kay Savage

6

1 reference

12 November 2017

Robin L Jones

8

1 reference

12 November 2017

publication date

11 June 2010

1 reference

12 November 2017

1 reference

12 November 2017

volume

23

1 reference

12 November 2017

issue

10

1 reference

12 November 2017

page(s)

1334-1345

1 reference

https://scigraph.springernature.com/pub.10.1038/modpathol.2010.121

12 November 2017

exact match

0 references

cites work

Homeostatic regulation of base excision repair by a p53-induced phosphatase: linking stress response pathways with DNA repair proteins.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Genetic alterations and oncogenic pathways associated with breast cancer subtypes

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

PPM1D is a potential therapeutic target in ovarian clear cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Tiling path genomic profiling of grade 3 invasive ductal breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Wip1-deficient mice are resistant to common cancer genes

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

WIP1 phosphatase is a negative regulator of NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Breast cancer staging: working with the sixth edition of the AJCC Cancer Staging Manual

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Nestin is expressed in basal-like and triple negative breast cancers.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Mutations in p53, p53 protein overexpression and breast cancer survival

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Alterations in the TOP2A and HER2 genes: association with adjuvant anthracycline sensitivity in human breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Novel patterns of genome rearrangement and their association with survival in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype?

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2010.121

7 January 2021

10.1038/MODPATHOL.2010.121

Identifiers

DOI

1 reference

Dimensions Publication ID

12 November 2017

1053543506

0 references

1 reference