(Q39859211)

15 September 2017

WIP1 phosphatase is a negative regulator of NF-kappaB signalling (English)

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15 September 2017

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Joanne Chew

1

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15 September 2017

Subhra Biswas

2

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15 September 2017

Sathyavageeswaran Shreeram

3

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15 September 2017

Mahathir Humaidi

4

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15 September 2017

Ee Tsin Wong

5

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15 September 2017

Manprit Kaur Dhillion

6

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15 September 2017

Hsiangling Teo

7

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15 September 2017

Amit Hazra

8

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15 September 2017

Cheok Chit Fang

9

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15 September 2017

Eduardo López-Collazo

10

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15 September 2017

Dmitry V Bulavin

11

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15 September 2017

Vinay Tergaonkar

12

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15 September 2017

19 April 2009

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15 September 2017

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15 September 2017

11

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15 September 2017

659-666

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15 September 2017

5

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https://scigraph.springernature.com/pub.10.1038/ncb1873

15 September 2017

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cites work

NF-kappaB regulation in the immune system

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Shared principles in NF-kappaB signaling

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

21 January 2018

1 reference

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

21 January 2018

1 reference

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

21 January 2018

1 reference

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

21 January 2018

1 reference

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop

21 January 2018

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Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

21 January 2018

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NF-kappaB RelA phosphorylation regulates RelA acetylation

21 January 2018

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

21 January 2018

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

21 January 2018

1 reference

The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression

21 January 2018

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

21 January 2018

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Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

21 January 2018

1 reference

NFkappaB pathway: a good signaling paradigm and therapeutic target

21 January 2018

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

21 January 2018

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

21 January 2018

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Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity

21 January 2018

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Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

21 January 2018

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COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

21 January 2018

1 reference

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

21 January 2018

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Shaping the nuclear action of NF-kappaB

21 January 2018

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RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling

21 January 2018

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Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.

21 January 2018

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Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity

21 January 2018

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Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A

21 January 2018

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The p60 tumor necrosis factor (TNF) receptor-associated kinase (TRAK) binds residues 344-397 within the cytoplasmic domain involved in TNF signaling

21 January 2018

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Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation.

21 January 2018

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Nutlin-3 inhibits the NFkappaB pathway in a p53-dependent manner: implications in lung cancer therapy.

21 January 2018

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Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

21 January 2018

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Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.

21 January 2018

1 reference

Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.

21 January 2018

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12 December 2020

Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites

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12 December 2020

Protein phosphatase 2A interacts with and directly dephosphorylates RelA

1 reference

12 December 2020

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

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12 December 2020

Regulation of NF-kappaB action by reversible acetylation

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12 December 2020

Identifiers

DOI

10.1038/NCB1873

1 reference

15 September 2017

1 reference