(Q43636970)

25 November 2017

title

Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol (English)

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25 November 2017

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4

C Schneider

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25 November 2017

K R Kozak

1

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25 November 2017

J J Prusakiewicz

series ordinal

2

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25 November 2017

S W Rowlinson

series ordinal

3

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25 November 2017

L J Marnett

series ordinal

5

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25 November 2017

language of work or name

English

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publication date

11 June 2001

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Journal of Biological Chemistry

25 November 2017

published in

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25 November 2017

volume

276

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25 November 2017

issue

32

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25 November 2017

page(s)

30072-30077

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Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

25 November 2017

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Prostaglandin G/H synthase isoenzyme 2 expression in fibroblasts: regulation by dexamethasone, mitogens, and oncogenes

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21 January 2018

Cyclooxygenases 1 and 2

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Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

21 January 2018

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Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation

21 January 2018

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Cloning and expression of rat prostaglandin endoperoxide synthase (cyclooxygenase)-2 cDNA.

21 January 2018

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Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2.

21 January 2018

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Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

21 January 2018

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Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: effect of the alcohol modifier.

21 January 2018

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Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

21 January 2018

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

21 January 2018

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Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

21 January 2018

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The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

21 January 2018

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Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site

21 January 2018

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The productive conformation of arachidonic acid bound to prostaglandin synthase

21 January 2018

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

21 January 2018

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Molecular cloning, functional expression, and selective regulation of ovine prostaglandin H synthase-2.

21 January 2018

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A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

21 January 2018

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Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents

21 January 2018

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Structural insights into the stereochemistry of the cyclooxygenase reaction

21 January 2018

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Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid

21 January 2018

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Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2

21 January 2018

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Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete

21 January 2018

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Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

21 January 2018

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The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region

21 January 2018

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Rapid inactivation of prostaglandin endoperoxide synthases by N-(carboxyalkyl)maleimides

21 January 2018

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The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs

21 January 2018

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Altered sensitivity of aspirin-acetylated prostaglandin G/H synthase-2 to inhibition by nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

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Stereospecificity of hydrogen abstraction in the conversion of arachidonic acid to 15R-HETE by aspirin-treated cyclooxygenase-2. Implications for the alignment of substrate in the active site

21 January 2018

1 reference

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Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104467200

21 January 2018

Identifiers

DOI

10.1074/JBC.M104467200

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25 November 2017

1 reference