(Q43895807)

27 November 2017

title

Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer (English)

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7

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Nico van Rooijen

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Karel Ulbrich

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Kerry D Fisher

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object named as

Kerry D Fisher

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Ashley Hale

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Nicola K Green

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Ryan Cawood

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Sam Illingworth

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Chris Herbert

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Terry Hermiston

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Karel Ulbrich

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Leonard W Seymour

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publication date

18 June 2012

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volume

7

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issue

11

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page(s)

1683-1695

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Cotton rat tumor model for the evaluation of oncolytic adenoviruses.

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cites work

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Intratumoral expression of a fusogenic membrane glycoprotein enhances the efficacy of replicating adenovirus therapy

21 January 2018

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

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Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer

21 January 2018

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An oncolytic adenovirus vector combining enhanced cell-to-cell spreading, mediated by the ADP cytolytic protein, with selective replication in cancer cells with deregulated wnt signaling

21 January 2018

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

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Oncolytic adenovirus that overproduces ADP and replicates selectively in tumors due to hTERT promoter-regulated E4 gene expression

21 January 2018

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Blood clearance rates of adenovirus type 5 in mice

21 January 2018

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Adenovirus serotype 5 hexon mediates liver gene transfer

21 January 2018

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Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates

21 January 2018

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Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer

21 January 2018

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Rapid Kupffer cell death after intravenous injection of adenovirus vectors

21 January 2018

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Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

21 January 2018

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Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

21 January 2018

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Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

21 January 2018

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Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy

21 January 2018

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HPMA copolymers for masking and retargeting of therapeutic viruses.

21 January 2018

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Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells

21 January 2018

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Quantitation of adenovirus DNA and virus particles with the PicoGreen fluorescent Dye.

21 January 2018

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Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide].

21 January 2018

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N-(2-Hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice

21 January 2018

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

21 January 2018

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Infection of Mouse Liver by Human Adenovirus Type 5

21 January 2018

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MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity

21 January 2018

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A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

21 January 2018

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Intravascular adenoviral agents in cancer patients: lessons from clinical trials

21 January 2018

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Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

21 January 2018

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Mouse myocardial first-pass perfusion MR imaging

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/NNM.12.50

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27 November 2017

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