(Q43917782)

18337420

28 November 2017

title

P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain (English)

1 reference

28 November 2017

0 references

0 references

6

Koichi Noguchi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

1

Kimiko Kobayashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

author name string

Hiroki Yamanaka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

Tetsuo Fukuoka

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

Yi Dai

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

Koichi Obata

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

language of work or name

English

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publication date

1 March 2008

1 reference

18337420

28 November 2017

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

16 May 2020

page(s)

2892-2902

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

Synaptic corelease of ATP and GABA in cultured spinal neurons

16 May 2020

cites work

1 reference

12 December 2020

Activation of mouse microglial cells affects P2 receptor signaling

1 reference

12 December 2020

Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation

1 reference

12 December 2020

P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes.

1 reference

12 December 2020

Neuronal plasticity: increasing the gain in pain

1 reference

12 December 2020

Advances in signalling by extracellular nucleotides. the role and transduction mechanisms of P2Y receptors

1 reference

12 December 2020

Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain

1 reference

12 December 2020

The role of neuroinflammation and neuroimmune activation in persistent pain

1 reference

12 December 2020

Identification of the platelet ADP receptor targeted by antithrombotic drugs

1 reference

12 December 2020

Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors.

1 reference

12 December 2020

Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia

1 reference

12 December 2020

Glial activation: a driving force for pathological pain

1 reference

12 December 2020

Spinal cord glia: new players in pain

1 reference

12 December 2020

ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord.

1 reference

12 December 2020

Blockade of adenosine diphosphate receptors P2Y(12) and P2Y(1) is required to inhibit platelet aggregation in whole blood under flow

1 reference

12 December 2020

Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats

1 reference

12 December 2020

Microglia as a source and target of cytokines

1 reference

12 December 2020

Role of p38 and p44/42 mitogen-activated protein kinases in microglia

1 reference

12 December 2020

1 reference

12 December 2020

P2Y receptor-mediated inhibition of voltage-dependent Ca2+ channels in rat dorsal root ganglion neurons

1 reference

12 December 2020

Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation.

1 reference

12 December 2020

Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury

1 reference

12 December 2020

Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.

1 reference

12 December 2020

Glial neuronal signaling in the central nervous system

1 reference

12 December 2020

Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons

1 reference

12 December 2020

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

1 reference

12 December 2020

Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2

1 reference

12 December 2020

Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models

1 reference

12 December 2020

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

1 reference

12 December 2020

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

1 reference

12 December 2020

Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing

1 reference

12 December 2020

Release of BDNF and GABA in the dorsal horn of neuropathic rats

1 reference

12 December 2020

Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain.

1 reference

12 December 2020

Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

1 reference

12 December 2020

Glia: a novel drug discovery target for clinical pain

1 reference

12 December 2020

Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

1 reference

12 December 2020

Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury

1 reference

12 December 2020

The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury

1 reference

12 December 2020

Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia

1 reference

12 December 2020

MAPK activation in nociceptive neurons and pain hypersensitivity

1 reference

12 December 2020

Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions

1 reference

12 December 2020

Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia

1 reference

12 December 2020

Cell signaling and the genesis of neuropathic pain

1 reference

12 December 2020

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

1 reference

12 December 2020

Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat

1 reference

12 December 2020

Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

1 reference

12 December 2020

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

1 reference

12 December 2020

Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38.

1 reference

12 December 2020

Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain

1 reference

12 December 2020

Role of the immune system in chronic pain.

1 reference

12 December 2020

Inhibition of p38 mitogen-activated protein kinase attenuates interleukin-1beta-induced thermal hyperalgesia and inducible nitric oxide synthase expression in the spinal cord

1 reference

12 December 2020

Co-activation of P2Y2 receptor and TRPV channel by ATP: implications for ATP induced pain

1 reference

12 December 2020

The function of microglia through purinergic receptors: neuropathic pain and cytokine release

1 reference

12 December 2020

Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia

1 reference

12 December 2020

A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

1 reference

12 December 2020

Purinergic receptors activating rapid intracellular Ca increases in microglia

1 reference

12 December 2020

Purinoceptors in microglia and neuropathic pain

1 reference

12 December 2020

Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord

1 reference

12 December 2020

P2X receptors as cell-surface ATP sensors in health and disease

1 reference

12 December 2020

Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury.

1 reference

12 December 2020

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

1 reference

12 December 2020

Protein kinases as potential targets for the treatment of pathological pain

1 reference

12 December 2020

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

1 reference

12 December 2020

Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis

1 reference

12 December 2020

ATP-induced chemotaxis of microglial processes requires P2Y receptor-activated initiation of outward potassium currents

1 reference

12 December 2020

Physiology and pathophysiology of purinergic neurotransmission

1 reference

12 December 2020

1 reference

12 December 2020

Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain.

1 reference

12 December 2020

A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury.

1 reference

12 December 2020

ATP release from dorsal spinal cord synaptosomes: characterization and neuronal origin

1 reference

12 December 2020

A novel P2-purinoceptor expressed by a subpopulation of astrocytes from the dorsal spinal cord of the rat.

1 reference

12 December 2020

ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord

1 reference

12 December 2020

Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

1 reference

12 December 2020

P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors

1 reference

12 December 2020

P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase c/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord

1 reference

12 December 2020

ATP P2x receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats

1 reference

12 December 2020

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

1 reference

12 December 2020

10.1523/JNEUROSCI.5589-07.2008

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670682&resulttype=core&format=json

release_rvepbo7fybdcfnbjcrfwswkhoe

16 May 2020

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24 November 2022

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16 May 2020

18337420

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