(Q44306252)

1 December 2017

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title

Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu. (English)

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1 December 2017

3

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1 December 2017

2

Eric Huntzinger

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1 December 2017

Felix Tritschler

1

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1 December 2017

9 April 2010

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Nature Reviews Molecular Cell Biology

1 December 2017

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1 December 2017

11

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1 December 2017

379-384

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1 December 2017

5

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https://scigraph.springernature.com/pub.10.1038/nrm2885

1 December 2017

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cites work

Disruption of GW bodies impairs mammalian RNA interference

1 reference

A role for the P-body component GW182 in microRNA function

21 January 2018

1 reference

Getting to the root of miRNA-mediated gene silencing

21 January 2018

1 reference

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

31 March 2020

1 reference

Origins and Mechanisms of miRNAs and siRNAs

31 March 2020

1 reference

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

31 March 2020

1 reference

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression

31 March 2020

1 reference

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

31 March 2020

1 reference

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

31 March 2020

1 reference

The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

31 March 2020

1 reference

The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans.

31 March 2020

1 reference

Identification of novel argonaute-associated proteins

31 March 2020

1 reference

A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

31 March 2020

1 reference

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

31 March 2020

1 reference

GW182 family proteins are crucial for microRNA-mediated gene silencing

31 March 2020

1 reference

The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing

31 March 2020

1 reference

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

31 March 2020

1 reference

Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins

31 March 2020

1 reference

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

31 March 2020

1 reference

A C-terminal silencing domain in GW182 is essential for miRNA function

31 March 2020

1 reference

Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila

31 March 2020

1 reference

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

31 March 2020

1 reference

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

31 March 2020

1 reference

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.

31 March 2020

1 reference

Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing

31 March 2020

1 reference

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins

31 March 2020

1 reference

The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing

31 March 2020

1 reference

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

31 March 2020

1 reference

Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

31 March 2020

1 reference

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

31 March 2020

1 reference

RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.

31 March 2020

1 reference

Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin.

31 March 2020

1 reference

The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release

31 March 2020

1 reference

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

31 March 2020

1 reference

Dual interactions of the translational repressor Paip2 with poly(A) binding protein

31 March 2020

1 reference

Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase

31 March 2020

1 reference

Regulation of poly(A)-binding protein through PABP-interacting proteins.

31 March 2020

1 reference

Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein

31 March 2020

1 reference

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

31 March 2020

1 reference

The mechanism of eukaryotic translation initiation and principles of its regulation

31 March 2020

1 reference

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation

31 March 2020

1 reference

Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression

31 March 2020

1 reference

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

31 March 2020

1 reference

Deadenylation is a widespread effect of miRNA regulation

31 March 2020

1 reference

MicroRNAs direct rapid deadenylation of mRNA

31 March 2020

1 reference

A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding

31 March 2020

1 reference

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

31 March 2020

1 reference

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

31 March 2020

1 reference

P bodies: at the crossroads of post-transcriptional pathways

31 March 2020

1 reference

P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

31 March 2020

1 reference

Survey on the PABC recognition motif PAM2.

31 March 2020

1 reference

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20379206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM2885

1 reference

1 December 2017

1 reference

PubMed ID

20379206