(Q44348986)

English

Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid

scientific article published in July 2003

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scholarly article

1 reference

Europe PubMed Central

2 December 2017

Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid (English)

1 reference

Europe PubMed Central

2 December 2017

1 reference

based on heuristic

inferred from title

5

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Europe PubMed Central

2 December 2017

author name string

Payman Nasr

1

1 reference

Europe PubMed Central

2 December 2017

Hemamalini I Gursahani

2

1 reference

Europe PubMed Central

2 December 2017

Zhen Pang

3

1 reference

Europe PubMed Central

2 December 2017

Vimala Bondada

4

1 reference

Europe PubMed Central

2 December 2017

Robert W Hadley

6

1 reference

Europe PubMed Central

2 December 2017

James W Geddes

7

1 reference

Europe PubMed Central

2 December 2017

publication date

1 July 2003

1 reference

Europe PubMed Central

2 December 2017

Neurochemistry International

1 reference

Europe PubMed Central

2 December 2017

43

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Europe PubMed Central

2 December 2017

2

1 reference

Europe PubMed Central

2 December 2017

89-99

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Europe PubMed Central

2 December 2017

Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative excitotoxic hypotheses

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial participation in the intracellular Ca2+ network

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Excitotoxic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

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PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondria as the central control point of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Release of Ca2+ from the sarcoplasmic reticulum increases mitochondrial [Ca2+] in rat pulmonary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Calpain activation in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Hippocampal damage and cytoskeletal disruption resulting from impaired energy metabolism. Implications for Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondria and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

3-Nitropropionic acid exacerbates N-methyl-D-aspartate toxicity in striatal culture by multiple mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic (energy deficient) brain damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Acute and chronic alterations in calcium homeostasis in 3-nitropropionic acid-treated human NT2-N neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: the roles of N-methyl-D-aspartate glutamate receptors and mitochondrial calcium overload.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular and functional properties of a calpain activator protein specific for mu-isoforms.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Properties and intracellular localization of calpain activator protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Visualization of NMDA receptor-induced mitochondrial calcium accumulation in striatal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial free Ca2+ concentration in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Calpastatin subdomains A and C are activators of calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Towards an understanding of the role of glutamate in neurodegenerative disorders: energy metabolism and neuropathology

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

NMDA receptor involvement in toxicity to dopamine neurons in vitro caused by the succinate dehydrogenase inhibitor 3-nitropropionic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

based on heuristic

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Mitochondrial Ca(2+)homeostasis in the regulation of apoptotic and necrotic cell deaths

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900229-2

7 January 2021

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Identifiers

10.1016/S0197-0186(02)00229-2

1 reference

Europe PubMed Central

2 December 2017

1 reference

Europe PubMed Central

2 December 2017

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