(Q44117680)

30 November 2017

Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons (English)

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30 November 2017

5

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30 November 2017

8

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30 November 2017

7

Chiara Zuccato

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Michela Matteoli

object named as

Michela Matteoli

6

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author name string

Donato Goffredo

1

1 reference

30 November 2017

Dorotea Rigamonti

2

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30 November 2017

Marzia Tartari

3

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30 November 2017

Alberto De Micheli

4

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30 November 2017

language of work or name

English

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publication date

27 August 2002

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Journal of Biological Chemistry

30 November 2017

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30 November 2017

277

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30 November 2017

39594-39598

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30 November 2017

42

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Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

30 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Modeling Huntington's disease in cells, flies, and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Loss of normal huntingtin function: new developments in Huntington's disease research

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Calpain and caspase: can you tell the difference?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Bioenergetics in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

NMDA receptor function in mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Specific proteolysis of the NR2 subunit at multiple sites by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Expression of NMDA receptor-1 (NR1) and huntingtin in striatal neurons which colocalize somatostatin, neuropeptide Y, and NADPH diaphorase: a double-label histochemical and immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C200353200

21 January 2018

Identifiers

DOI

10.1074/JBC.C200353200

1 reference

30 November 2017

1 reference