(Q44374517)

2 December 2017

title

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria (English)

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2 December 2017

2

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2 December 2017

9

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2 December 2017

13

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2 December 2017

Alain Baulard

6

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Camille Locht

11

object named as

Camille Locht

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2 December 2017

1

Laurent Kremer

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2 December 2017

Hector R Morbidoni

3

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2 December 2017

Catherine Vilchèze

4

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2 December 2017

William N Maughan

5

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2 December 2017

Shiao-Chun Tu

7

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2 December 2017

Nadine Honoré

8

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2 December 2017

James C Sacchettini

10

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2 December 2017

William R Jacobs

12

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2 December 2017

language of work or name

English

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publication date

24 March 2003

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Journal of Biological Chemistry

2 December 2017

published in

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2 December 2017

volume

278

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2 December 2017

issue

23

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2 December 2017

page(s)

20547-20554

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The chemical approach to the control of tuberculosis

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inhibition by Isoniazid of Synthesis of Mycolic Acids in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Scanning electron microscopy of the H37Ra strain of Mycobacterium tuberculosis exposed to isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Lipid biosynthesis as a target for antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Current status and future development of antitubercular chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Effects of Ethionamide and Isoxyl on Mycolic Acid Synthesis in Mycobacterium tuberculosis bcg

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Activation of the pro-drug ethionamide is regulated in mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Syntheses and evaluation of benzodiazaborine compounds against M. tuberculosis H37Rv in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

A mechanism of drug action revealed by structural studies of enoyl reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Triclosan: a widely used biocide and its link to antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Defining and combating the mechanisms of triclosan resistance in clinical isolates of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Isoniazid activation defects in recombinant Mycobacterium tuberculosis catalase-peroxidase (KatG) mutants evident in InhA inhibitor production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

New use of BCG for recombinant vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Temperature-induced changes in the cell-wall components of Mycobacterium thermoresistibile

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

The role of Mn(II)-peroxidase activity of mycobacterial catalase-peroxidase in activation of the antibiotic isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Action mechanism of antitubercular isoniazid. Activation by Mycobacterium tuberculosis KatG, isolation, and characterization of inha inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Effect of side-chain structure on inhibition of yeast fatty-acid synthase by cerulenin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Mechanism of action of cerulenin on fatty acid synthetase. Effect of cerulenin on iodoacetamide-induced malonyl-CoA decarboxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

Acyl carrier protein from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302435200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302435200

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2 December 2017

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