(Q44386993)

2 December 2017

title

Csk regulates integrin-mediated signals: involvement of differential activation of ERK and Akt. (English)

1 reference

2 December 2017

Jianguo Gu

1

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2 December 2017

Shigeyuki Nada

series ordinal

2

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2 December 2017

Masato Okada

series ordinal

3

1 reference

2 December 2017

Kiyotoshi Sekiguchi

series ordinal

4

1 reference

2 December 2017

language of work or name

English

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publication date

1 April 2003

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Biochemical and Biophysical Research Communications

2 December 2017

published in

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2 December 2017

volume

303

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2 December 2017

issue

3

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2 December 2017

page(s)

973-977

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

2 December 2017

1 reference

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Integrin signaling revisited

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Src family kinases are required for integrin but not PDGFR signal transduction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Role of focal adhesion kinase in integrin signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Csk suppression of Src involves movement of Csk to sites of Src activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Csk, a critical link of g protein signals to actin cytoskeletal reorganization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Isolation and characterization of laminin-10/11 secreted by human lung carcinoma cells. laminin-10/11 mediates cell adhesion through integrin alpha3 beta1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Purification and characterization of human laminin-8. Laminin-8 stimulates cell adhesion and migration through alpha3beta1 and alpha6beta1 integrins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Phosphorylation and regulation of Raf by Akt (protein kinase B)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Regulation of Akt/PKB activation by tyrosine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900468-6

10.1016/S0006-291X(03)00468-6

7 January 2021

Identifiers

DOI

1 reference

2 December 2017

1 reference