(Q44428795)

English

3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones

scientific article published in May 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 December 2017

3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Fabrizio Manetti

1

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Europe PubMed Central

PubMed publication ID

2 December 2017

5

object named as

Maurizio Botta

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

author name string

Stefano Forli

2

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Europe PubMed Central

PubMed publication ID

2 December 2017

Laura Maccari

3

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Europe PubMed Central

PubMed publication ID

2 December 2017

Federico Corelli

4

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Europe PubMed Central

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2 December 2017

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publication date

1 May 2003

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Europe PubMed Central

PubMed publication ID

2 December 2017

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Europe PubMed Central

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2 December 2017

58

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Europe PubMed Central

PubMed publication ID

2 December 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

357-361

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Europe PubMed Central

PubMed publication ID

2 December 2017

Peripheral neuropathy from taxol and cisplatin combination chemotherapy: clinical and electrophysiological studies

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The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice

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Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells

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7 January 2021

Refined structure of alpha beta-tubulin at 3.5 A resolution

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7 January 2021

A common pharmacophore for cytotoxic natural products that stabilize microtubules

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7 January 2021

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

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7 January 2021

Comparative molecular field analysis (coMFA) study of epothilones-tubulin depolymerization inhibitors: pharmacophore development using 3D QSAR methods.

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7 January 2021

A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone

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The oxetane ring in taxol.

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General and recent aspects of the chemistry and structure-activity relationships of taxoids

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Relationships between the structure of taxol analogs and their antimitotic activity

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7 January 2021

Biologically active taxol analogs with deleted A-ring side chain substituents and variable C-2' configurations

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7 January 2021

Synthesis and evaluation of C-seco paclitaxel analogues

1 reference

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7 January 2021

Chemical synthesis and biological properties of pyridine epothilones

1 reference

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7 January 2021

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

1 reference

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7 January 2021

Chemical Biology of Epothilones

1 reference

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7 January 2021

Identifiers

10.1016/S0014-827X(03)00052-1

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

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