(Q44581995)

4 December 2017

title

Selection biases the prevalence and type of epistasis along adaptive trajectories (English)

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4 December 2017

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2

Joshua B Plotkin

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4 December 2017

Jeremy A Draghi

1

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4 December 2017

language of work or name

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4 July 2013

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4 December 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

Evolution

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4 December 2017

volume

67

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4 December 2017

issue

11

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4 December 2017

page(s)

3120-3131

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In the light of directed evolution: pathways of adaptive protein evolution

4 December 2017

cites work

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Permissive secondary mutations enable the evolution of influenza oseltamivir resistance

21 January 2018

1 reference

Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

21 January 2018

1 reference

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

21 January 2018

1 reference

Colloquium papers: Adaptive landscapes and protein evolution

21 January 2018

1 reference

Diminishing returns epistasis among beneficial mutations decelerates adaptation

21 January 2018

1 reference

Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape.

21 January 2018

1 reference

Epistasis increases the rate of conditionally neutral substitution in an adapting population

21 January 2018

1 reference

Molecular Evolution Over the Mutational Landscape

21 January 2018

1 reference

Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme

21 January 2018

1 reference

Towards a general theory of adaptive walks on rugged landscapes

21 January 2018

1 reference

The NK model of rugged fitness landscapes and its application to maturation of the immune response

21 January 2018

1 reference

Negative epistasis between beneficial mutations in an evolving bacterial population

21 January 2018

1 reference

Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape

21 January 2018

1 reference

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

21 January 2018

1 reference

Pervasive cryptic epistasis in molecular evolution

21 January 2018

1 reference

Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1

21 January 2018

1 reference

Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance

21 January 2018

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Constructing and analyzing the fitness landscape of an experimental evolutionary process

21 January 2018

1 reference

Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli.

21 January 2018

1 reference

Epistasis between beneficial mutations and the phenotype-to-fitness Map for a ssDNA virus

21 January 2018

1 reference

Initial mutations direct alternative pathways of protein evolution

21 January 2018

1 reference

Quantitative analyses of empirical fitness landscapes

21 January 2018

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Positive epistasis drives the acquisition of multidrug resistance

21 January 2018

1 reference

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 January 2018

1 reference

The rate at which asexual populations cross fitness valleys

21 January 2018

1 reference

Second-order selection for evolvability in a large Escherichia coli population

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/EVO.12192

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4 December 2017

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