(Q44641786)

English

PDNF, a human parasite-derived mimic of neurotrophic factors, prevents caspase activation, free radical formation, and death of dopaminergic cells exposed to the Parkinsonism-inducing neurotoxin MPP+

scientific article published on November 6, 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

PDNF, a human parasite-derived mimic of neurotrophic factors, prevents caspase activation, free radical formation, and death of dopaminergic cells exposed to the Parkinsonism-inducing neurotoxin MPP+ (English)

1 reference

10.1016/J.MOLBRAINRES.2003.08.012

https://api.crossref.org/works/10.1016/J.MOLBRAINRES.2003.08.012

28 March 2024

Parkinson's disease

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Marina V. Chuenkova

1

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14597229

28 March 2024

Miercio A. Pereira

2

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Europe PubMed Central

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28 March 2024

language of work or name

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14597229

28 March 2024

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1 November 2003

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4 December 2017

6 November 2003

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28 March 2024

full work available at URL

https://api.elsevier.com/content/article/PII:S0169328X03003759?httpAccept=text/xml

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10.1016/J.MOLBRAINRES.2003.08.012

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28 March 2024

https://api.elsevier.com/content/article/PII:S0169328X03003759?httpAccept=text/plain

1 reference

10.1016/J.MOLBRAINRES.2003.08.012

https://api.crossref.org/works/10.1016/J.MOLBRAINRES.2003.08.012

28 March 2024

Molecular Brain Research

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Europe PubMed Central

PubMed publication ID

4 December 2017

119

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Europe PubMed Central

PubMed publication ID

4 December 2017

1

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Europe PubMed Central

PubMed publication ID

4 December 2017

50-61

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Europe PubMed Central

PubMed publication ID

4 December 2017

BCL-2 is involved in preventing oxidant-induced cell death and in decreasing oxygen radical production.

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2

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1 reference

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1 reference

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1 reference

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1 reference

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DNA sequences encoding CD4+ and CD8+ T-cell epitopes are important for efficient protective immunity induced by DNA vaccination with a Trypanosoma cruzi gene

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1 reference

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1 reference

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Functional recovery in parkinsonian monkeys treated with GDNF

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1 reference

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1 reference

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Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

10.1016/J.MOLBRAINRES.2003.08.012

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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