(Q44650518)

5 December 2017

Constitutively active Gq/11-coupled receptors enable signaling by co-expressed G(i/o)-coupled receptors (English)

1 reference

5 December 2017

Constitutively active Gq/11-coupled Receptors Enable Signaling by Co-expressed Gi/o-coupled Receptors (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610092

31 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

author name string

Paola Casarosa

2

1 reference

5 December 2017

Henk Timmerman

3

1 reference

5 December 2017

Rob Leurs

5

1 reference

5 December 2017

Remko A. Bakker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610092

31 March 2024

Martine J. Smit

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610092

31 March 2024

language of work or name

English

0 references

publication date

10 November 2003

1 reference

full work available at URL

5 December 2017

http://www.jbc.org/article/S0021925820748398/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610092

https://api.elsevier.com/content/article/PII:S0021925820748398?httpAccept=text/xml

31 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

https://api.elsevier.com/content/article/PII:S0021925820748398?httpAccept=text/plain

31 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

https://syndication.highwire.org/content/doi/10.1074/jbc.M309200200

31 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Journal of Biological Chemistry

31 March 2024

published in

1 reference

5 December 2017

279

1 reference

5 December 2017

5152-5161

1 reference

5 December 2017

7

1 reference

Drug discovery: a historical perspective

5 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

G protein-coupled receptors. II. Mechanism of agonist activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Cross talk between beta-adrenergic and bradykinin B(2) receptors results in cooperative regulation of cyclic AMP accumulation and mitogen-activated protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Beta(2)-adrenergic receptors potentiate glucocorticoid receptor transactivation via G protein beta gamma-subunits and the phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Heterologous expression of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Drug efficacy at G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Inverse agonism and the regulation of receptor number

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Defects in G protein-coupled signal transduction in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Human 5-HT1B receptor stimulated inositol phospholipid hydrolysis in CHO cells: synergy with Gq-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Human chemokines: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Activation of the p38 and p42/p44 mitogen-activated protein kinase families by the histamine H(1) receptor in DDT(1)MF-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Role of G-protein beta gamma subunits in the augmentation of P2Y2 (P2U)receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Rhodopsin-family receptors associate with small G proteins to activate phospholipase D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-kappa B pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

The role of Rho in G protein-coupled receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Pertussis toxin-sensitive G proteins as mediators of the signal transduction pathways activated by cytomegalovirus infection of smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Inverse agonism gains weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

G alpha 16 couples chemoattractant receptors to NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309200200

Regulation of G protein function: implications for heart disease

21 January 2018

2

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

31 March 2024

13

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Agonist-independent regulation of constitutively active G-protein-coupled receptors

31 March 2024

14

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling.

31 March 2024

24

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways

31 March 2024

29

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

Chemokine receptors

30

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Guinea pig histamine H1 receptor. II. Stable expression in Chinese hamster ovary cells reveals the interaction with three major signal transduction pathways

31 March 2024

34

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

G(i)-dependent activation of c-Jun N-terminal kinase in human embryonal kidney 293 cells

31 March 2024

46

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Angiotensin II receptor coupling to phospholipase D is mediated by the betagamma subunits of heterotrimeric G proteins in vascular smooth muscle cells

31 March 2024

47

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Inhibition of cell differentiation by G alpha q in the renal epithelial cell line LLC-PK1.

31 March 2024

49

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

[Ca(2+)](i) oscillation frequency regulates agonist-stimulated NF-kappaB transcriptional activity

31 March 2024

50

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Preactivation permits subsequent stimulation of phospholipase C by G(i)-coupled receptors

31 March 2024

54

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Serotonin and vasoconstrictor synergism

31 March 2024

55

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells

31 March 2024

59

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt

31 March 2024

60

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

Molecular Pharmacology

63

60

857

Zhen

2001

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases

31 March 2024

65

1 reference

https://api.crossref.org/works/10.1074/JBC.M309200200

31 March 2024

Identifiers

1 reference

release_qs7bnmei5rff5b3vrybjjy7zri

5 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qs7bnmei5rff5b3vrybjjy7zri

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference