(Q44662103)

English

Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity

scientific article published on 19 November 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

hypocholesterolemia

0 references

1 reference

based on heuristic

inferred from title

author name string

Joseph Roitelman

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Danièle Masson

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Rachel Avner

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Corinne Ammon-Zufferey

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Anne Perez

5

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Yves Guyon-Gellin

6

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Craig L Bentzen

7

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Eric J Niesor

8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

0 references

publication date

19 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

6465-6473

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

A receptor-mediated pathway for cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Proteolysis and sterol regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

In vivo examination of membrane protein localization and degradation with green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Stimulation of bone formation in vitro and in rodents by statins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Impaired regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation in lovastatin-resistant cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Characterization of UT2 cells. The induction of peroxisomal 3-hydroxy-3-methylglutaryl-coenzyme a reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Acyl-coenzyme A:cholesterol acyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane dom

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The nuclear receptors FXR and LXRalpha: potential targets for the development of drugs affecting lipid metabolism and neoplastic diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Cycloheximide sensitivity in regulation of acyl coenzyme A:cholesterol acyltransferase activity in Chinese hamster ovary cells. 1. Effect of exogenous sterols

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

A simple and efficient procedure for the rapid homogenization of cultured animal cells grown in monolayer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308094200

21 January 2018

Identifiers

10.1074/JBC.M308094200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44662103&oldid=2031083379"