(Q44814644)

English

A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions

scientific article published on 23 March 2004

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

DNA polymerization

0 references

9

object named as

Bruno Canard

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

author name string

Jérôme Deval

1

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Jean-Marc Navarro

2

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Boulbaba Selmi

3

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Jérôme Courcambeck

4

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Joëlle Boretto

5

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Philippe Halfon

6

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Sarah Garrido-Urbani

7

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Josephine Sire

8

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

language of work or name

0 references

publication date

23 March 2004

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

25489-25496

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Targeting HIV: antiretroviral therapy and development of drug resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

The molecular mechanism of multidrug resistance by the Q151M human immunodeficiency virus type 1 reverse transcriptase and its suppression using alpha-boranophosphate nucleotide analogues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Fitness of drug resistant HIV-1: methodology and clinical implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Glutamic residue 438 within the protease-sensitive subdomain of HIV-1 reverse transcriptase is critical for heterodimer processing in viral particles.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

A quantitative assay for HIV DNA integration in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Hydration free energy a fragmental model and drug design

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Pyrimidine nucleotide and nucleic acid synthesis in human monocytes and macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Simultaneous determination of pyrimidine or purine deoxyribonucleoside triphosphates using a polymerase assay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313534200

21 January 2018

Identifiers

10.1074/JBC.M313534200

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44814644&oldid=2046957161"