(Q44846647)

6 December 2017

title

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events (English)

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6 December 2017

1

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6 December 2017

7

Katharina Gaus

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6 December 2017

4

Astrid Magenau

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6 December 2017

3

Jérémie Rossy

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6 December 2017

Dylan M Owen

2

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6 December 2017

Matthias Wehrmann

series ordinal

5

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6 December 2017

J Justin Gooding

series ordinal

6

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6 December 2017

language of work or name

English

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publication date

5 June 2011

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6 December 2017

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6 December 2017

volume

12

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6 December 2017

issue

7

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6 December 2017

page(s)

655-662

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

6 December 2017

cites work

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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

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Condensation of the plasma membrane at the site of T lymphocyte activation

21 January 2018

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High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells

21 January 2018

1 reference

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

21 January 2018

1 reference

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

21 January 2018

1 reference

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

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The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

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Signal transduction by lymphocyte antigen receptors

21 January 2018

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In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern.

21 January 2018

1 reference

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

21 January 2018

1 reference

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

21 January 2018

1 reference

Essential role of LAT in T cell development

21 January 2018

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Activation of T lymphocytes and the role of the adapter LAT.

21 January 2018

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The Importance of LAT in the Activation, Homeostasis, and Regulatory Function of T Cells

21 January 2018

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T cell antigen receptor signaling and immunological synapse stability require myosin IIA

21 January 2018

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T cell receptor signaling precedes immunological synapse formation

21 January 2018

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The immunological synapse balances T cell receptor signaling and degradation

21 January 2018

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TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

21 January 2018

1 reference

Imaging intracellular fluorescent proteins at nanometer resolution

21 January 2018

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Ultra-high resolution imaging by fluorescence photoactivation localization microscopy

21 January 2018

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Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)

21 January 2018

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Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes

21 January 2018

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Direct measurement of the evanescent field profile produced by objective-based total internal reflection fluorescence

21 January 2018

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Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells

21 January 2018

1 reference

21 January 2018

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Targeting quantum dots to surface proteins in living cells with biotin ligase

21 January 2018

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Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains

21 January 2018

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Palmitoylation of LAT contributes to its subcellular localization and stability

21 January 2018

1 reference

Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells.

21 January 2018

1 reference

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

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Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

21 January 2018

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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

21 January 2018

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Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse

21 January 2018

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Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment

21 January 2018

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Role of the LAT adaptor in T-cell development and Th2 differentiation

21 January 2018

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Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation

21 January 2018

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Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling

21 January 2018

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Selective accumulation of raft-associated membrane protein LAT in T cell receptor signaling assemblies

21 January 2018

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Functional implications of plasma membrane condensation for T cell activation

21 January 2018

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High resolution mapping of mast cell membranes reveals primary and secondary domains of Fc(epsilon)RI and LAT.

21 January 2018

1 reference

SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering

21 January 2018

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T-Cell Antigen Receptor-Induced Signaling Complexes: Internalization Via a Cholesterol-Dependent Endocytic Pathway

21 January 2018

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Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor

21 January 2018

1 reference

On the dynamics of TCR:CD3 complex cell surface expression and downmodulation

21 January 2018

1 reference

Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase

21 January 2018

1 reference

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

21 January 2018

1 reference

Immunology. The immunological synapse--a multitasking system

21 January 2018

1 reference

Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

21 January 2018

1 reference

Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21642986

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2049

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Dimensions Publication ID

6 December 2017

1040784844

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