(Q44848220)

6 December 2017

PTEN regulates Mdm2 expression through the P1 promoter (English)

1 reference

6 December 2017

Chun-Ju Chang

1

1 reference

6 December 2017

Daniel J Freeman

series ordinal

2

1 reference

6 December 2017

Hong Wu

series ordinal

3

1 reference

6 December 2017

language of work or name

English

0 references

publication date

16 April 2004

1 reference

Journal of Biological Chemistry

6 December 2017

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6 December 2017

279

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6 December 2017

29841-29848

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6 December 2017

28

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Amplification of a gene encoding a p53-associated protein in human sarcomas

6 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

The MDM2 gene amplification database

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

A functional p53-responsive intronic promoter is contained within the human mdm2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Mechanisms of p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Functions of the MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Mapping of the p53 and mdm-2 interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Genomic organization of the mouse double minute 2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Characterization of the 5' and 3' untranslated regions in murine mdm2 mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Mdm2: A regulator of cell growth and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Abnormal expression of MDM2 in prostate carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401488200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401488200

1 reference

6 December 2017

1 reference