(Q35572466)

8 August 2017

1 reference

title

Mdm2: A regulator of cell growth and death (English)

1 reference

8 August 2017

3

Ze'ev Ronai

0 references

Shoichi Takahashi

series ordinal

2

object named as

Shoichi Takahashi

1 reference

8 August 2017

Dania Alarcon Vargas

1

1 reference

8 August 2017

1 January 2003

1 reference

Advances in Cancer Research

8 August 2017

1 reference

8 August 2017

89

1 reference

8 August 2017

1-34

1 reference

Comprehensive analysis of genomic alterations in gliosarcoma and its two tissue components

8 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Conformation-dependent phosphorylation of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53-Mdm2--the affair that never ends

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdm2 binds p73 alpha without targeting degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Multiple roles of the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Alternative and aberrant splicing of MDM2 mRNA in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Transformation associated p53 protein is encoded by a gene on human chromosome 17.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Hypophosphorylation of Mdm2 augments p53 stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Abnormal expression of MDM-2 in breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2: life without p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The large T antigen of simian virus 40 binds and inactivates p53 but not p73.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The MDM2 oncoprotein binds specifically to RNA through its RING finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Regulation of p53 activity in nuclear bodies by a specific PML isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdm2 association with p53 targets its ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

JNK targets p53 ubiquitination and degradation in nonstressed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Identification of a sequence element from p53 that signals for Mdm2-targeted degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mutual dependence of MDM2 and MDMX in their functional inactivation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Protein-mediated nuclear export of RNA: 5S rRNA containing small RNPs in xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Biochemistry. All in the ubiquitin family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Localization of gene for human p53 tumour antigen to band 17p13.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Two cellular proteins that bind to wild-type but not mutant p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MdmX protects p53 from Mdm2-mediated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

pRB induces Sp1 activity by relieving inhibition mediated by MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Regulation of p63 function by Mdm2 and MdmX.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

TSG101 may be the prototype of a class of dominant negative ubiquitin regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Functional analysis and intracellular localization of p53 modified by SUMO-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Apoptotic and growth-promoting activity of E2F modulated by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The p53 and Mdm2 families in cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Human p53 gene localized to short arm of chromosome 17

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdm-2: "big brother" of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The organization and expression of the mdm2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 and MDMX bind and stabilize the p53-related protein p73

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

RETRACTED: Regulation of p53: intricate loops and delicate balances

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Prognostic factors in betel and tobacco related oral cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 mutational spectra and the role of methylated CpG sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Expression of MDM2 during mammary tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

SUMO-1 modification activates the transcriptional response of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Analysis of a protein-binding domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The expression of murine double minute 2 is a favorable prognostic marker in esophageal squamous cell carcinoma without p53 protein accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A novel protein with strong homology to the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53-independent role of MDM2 in TGF-beta1 resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 interacts with MDMX through their RING finger domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

A new human p53 homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 leans on its siblings

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 and MDMX can interact differently with ARF and members of the p53 family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

MDM2 suppresses p73 function without promoting p73 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Cyclin a-CDK phosphorylation regulates MDM2 protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The initial evaluation of non-peptidic small-molecule HDM2 inhibitors based on p53-HDM2 complex structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

Novel targets of Akt, p21(Cipl/WAF1), and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2901001-7

7 January 2021

10.1016/S0065-230X(03)01001-7

Identifiers

DOI

1 reference

8 August 2017

1 reference

PubMed ID

14587869