(Q45032460)

8 December 2017

cAMP-dependent oncogenic action of Rap1b in the thyroid gland (English)

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8 December 2017

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Fernando Ribeiro-Neto

1

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8 December 2017

Angelica Leon

2

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8 December 2017

Julie Urbani-Brocard

3

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8 December 2017

Liguang Lou

4

1 reference

8 December 2017

Abraham Nyska

5

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8 December 2017

Daniel L Altschuler

6

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8 December 2017

language of work or name

English

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publication date

25 August 2004

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Journal of Biological Chemistry

8 December 2017

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8 December 2017

279

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8 December 2017

45

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8 December 2017

46868-46875

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Cyclic AMP-dependent activation of Rap1b

8 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Role of Cyclic Nucleotides in Growth Control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Mitogenic and oncogenic properties of the small G protein Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Spatio-temporally controlled site-specific somatic mutagenesis in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Inhibition of thyrotropin response to thyrotropin-releasing hormone by small quantities of thyroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Relationships between cell division, expression of growth factors and microcirculation in the thyroids of Tg-A2aR transgenic mice and patients with Graves' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Reversibility of the malignant phenotype in monoclonal tumours in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Role of integrins in cell invasion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Ras GTPases: integrins' friends or foes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Dissemination and growth of cancer cells in metastatic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

The organ microenvironment and cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Ras and Rap1: two highly related small GTPases with distinct function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Oncogenic potential of guanine nucleotide stimulatory factor alpha subunit in thyroid glands of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Molecular pathobiology of thyroid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

A bad rap: Rap1 signaling and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Role of the Rap1 GTPase in astrocyte growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

DOCK4, a GTPase activator, is disrupted during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406858200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406858200

1 reference

8 December 2017

1 reference