(Q45049610)

8 December 2017

title

Inhibition of HIV-1 virus replication using small soluble Tat peptides (English)

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8 December 2017

John D Wade

5

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author name string

Emmanuel Agbottah

1

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8 December 2017

Naigong Zhang

2

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8 December 2017

Shabnam Dadgar

3

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8 December 2017

Anne Pumfery

4

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8 December 2017

Chen Zeng

6

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8 December 2017

Fatah Kashanchi

7

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8 December 2017

language of work or name

English

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publication date

14 November 2005

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8 December 2017

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8 December 2017

volume

345

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8 December 2017

issue

2

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8 December 2017

page(s)

373-389

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Antiviral activity of CYC202 in HIV-1-infected cells

8 December 2017

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Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

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A single intermolecular contact mediates intramolecular stabilization of both RNA and protein

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Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription

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Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators

7 January 2021

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HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA.

7 January 2021

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Tat stimulates cotranscriptional capping of HIV mRNA.

7 January 2021

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Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain

7 January 2021

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The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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CDK9 (PITALRE): a multifunctional cdc2-related kinase

7 January 2021

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Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes

7 January 2021

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Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones

7 January 2021

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Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA

7 January 2021

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HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter

7 January 2021

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Fine resolution of histones by two-dimensional polyacrylamide gel electrophoresis: developmental implications.

7 January 2021

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The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation

7 January 2021

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Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR.

7 January 2021

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Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD

7 January 2021

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Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter

7 January 2021

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Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells

7 January 2021

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CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

7 January 2021

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Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes

7 January 2021

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Interactions of human immunodeficiency virus type 1 transactivator of transcription protein with signal transduction pathways

7 January 2021

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Cyclin E ablation in the mouse

7 January 2021

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Structural and dynamic properties of the HIV-1 tat transduction domain in the free and heparin-bound states

7 January 2021

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A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition

7 January 2021

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Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme

7 January 2021

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

7 January 2021

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Inhibition of gene expression in human cells through small molecule-RNA interactions

7 January 2021

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Domains in the SPT5 protein that modulate its transcriptional regulatory properties

7 January 2021

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Inhibition of HIV-1 replication by an anti-tat hammerhead ribozyme

7 January 2021

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Modulation of HIV-1 replication by RNA interference

7 January 2021

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Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2.

7 January 2021

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7 January 2021

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Electroporation of viral transactivator proteins into lymphocyte suspension cells

7 January 2021

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Inhibition of HIV-1 transcription and virus replication using soluble Tat peptide analogs

7 January 2021

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HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors

7 January 2021

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Tat-SF1 protein associates with RAP30 and human SPT5 proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

7 January 2021

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Pharmacology and clinical experience with saquinavir

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Identification of cdk2 binding sites on the p27Kip1 cyclin-dependent kinase inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

The cdk2 binding domain of p27Kip correlates with the inhibition of the kinase activity of cdk2/cyclin complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

RNAi could hold promise in the treatment of HIV

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Transcriptional regulation by targeted recruitment of cyclin-dependent CDK9 kinase in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

An extensive network of coupling among gene expression machines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

HIV-1 Tat protein trans-activates transcription in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

In vitro selection of HIV-1 TAR variants by the Tat protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Cyclopropane-derived peptidomimetics. Design, synthesis, evaluation, and structure of novel HIV-1 protease inhibitors

7 January 2021

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Cell proliferation without cyclin E-CDK2

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Functional coupling of capping and transcription of mRNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Integrating mRNA processing with transcription

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Chromatin remodeling and modification during HIV-1 Tat-activated transcription

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

7 January 2021

Peptidomimetic design

1 reference

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HIV-1 Tat protein can transactivate a heterologous TATAA element independent of viral promoter sequences and the trans-activation response element

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Regulatory functions of Cdk9 and of cyclin T1 in HIV Tat transactivation pathway gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Dynamic association of capping enzymes with transcribing RNA polymerase II

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Role of viral regulatory and accessory proteins in HIV-1 replication

7 January 2021

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Aspartate and glutamate mimetic structures in biologically active compounds

7 January 2021

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Aspartic protease inhibitors

7 January 2021

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Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

7 January 2021

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Inhibition of acute-, latent-, and chronic-phase human immunodeficiency virus type 1 (HIV-1) replication by a bistriazoloacridone analog that selectively inhibits HIV-1 transcription

7 January 2021

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Evidence for Functional Interaction between the HIV-1 Tat Transactivator and the TATA Box Binding Proteinin Vivo

7 January 2021

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Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors

7 January 2021

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Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

The Cyclin E/Cdk2 Substrate and Cajal Body Component p220NPATActivates Histone Transcription through a Novel LisH-Like Domain

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.09.062

Transcription elongation factor hSPT5 stimulates mRNA capping

7 January 2021

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Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat

7 January 2021

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

7 January 2021

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Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

7 January 2021

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Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

7 January 2021

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TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription

7 January 2021

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Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription

7 January 2021

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Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex

7 January 2021

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Host factors in the pathogenesis of HIV disease

7 January 2021

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7 January 2021

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

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7 January 2021

Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate

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7 January 2021

Aspartic protease inhibitors. An integrated approach for the design andsynthesis of diaminodiol-based peptidomimetics

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7 January 2021

10.1016/J.VIROL.2005.09.062

Identifiers

DOI

1 reference

8 December 2017

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