(Q45235052)

11 December 2017

Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes (English)

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11 December 2017

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S M Uriarte

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11 December 2017

S Joshi-Barve

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11 December 2017

Z Song

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11 December 2017

R Sahoo

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11 December 2017

L Gobejishvili

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11 December 2017

V R Jala

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11 December 2017

B Haribabu

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11 December 2017

C McClain

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11 December 2017

S Barve

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11 December 2017

1 March 2005

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Cell Death & Differentiation

11 December 2017

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12

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3

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11 December 2017

233-242

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401549

11 December 2017

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cites work

The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3

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Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

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Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

21 January 2018

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21 January 2018

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AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

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Unravelling the activation mechanisms of protein kinase B/Akt

21 January 2018

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Activation-induced cell death in T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

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Inhibition of death receptor signals by cellular FLIP

21 January 2018

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I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

21 January 2018

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Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

21 January 2018

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The CD95(APO-1/Fas) DISC and beyond

21 January 2018

1 reference

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Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort

21 January 2018

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Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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The Bcl-2 protein family: arbiters of cell survival

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Fas (CD95/Apo-1) ligand regulation in T cell homeostasis, cell-mediated cytotoxicity and immune pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Jurkat T cells and development of the T-cell receptor signalling paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Serum bioactive lysophospholipids prevent TRAIL-induced apoptosis via PI3K/Akt-dependent cFLIP expression and Bad phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Eicosapentaenoic acid protects endothelial cells against anoikis through restoration of cFLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Theileria parva-transformed T cells show enhanced resistance to Fas/Fas ligand-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Comparison of seven quantitative assays to assess lymphocyte cell death during HIV infection: measurement of induced apoptosis in anti-Fas-treated Jurkat cells and spontaneous apoptosis in peripheral blood mononuclear cells from children infected wi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401549

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Identifiers

DOI

10.1038/SJ.CDD.4401549

1 reference

Dimensions Publication ID

11 December 2017

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