(Q45292704)

English

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model

scientific article published on 29 April 2013

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model (English)

1 reference

Europe PubMed Central

11 December 2017

Huntington's disease

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phosphorylation

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

11 December 2017

6

1 reference

Europe PubMed Central

11 December 2017

Esther Perez-Navarro

object named as

Esther Pérez-Navarro

7

0 references

object named as

Shiraz Tyebji

5

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author name string

Ana Saavedra

2

1 reference

Europe PubMed Central

11 December 2017

Olga Carretón

3

1 reference

Europe PubMed Central

11 December 2017

Helena Arumí

4

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Europe PubMed Central

11 December 2017

publication date

29 April 2013

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Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

23

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Europe PubMed Central

11 December 2017

8

1 reference

Europe PubMed Central

11 December 2017

684-695

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Europe PubMed Central

11 December 2017

Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Improving memory: a role for phosphodiesterases

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Ethanol-induced translocation of cAMP-dependent protein kinase to the nucleus. Mechanism and functional consequences

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Immunohistochemical localization of phosphodiesterase 10A in multiple mammalian species.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Protein phosphatase 1 is a molecular constraint on learning and memory.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

The PDE10A inhibitor, papaverine, differentially activates ERK in male and female rat striatal slices

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Chronic suppression of phosphodiesterase 10A alters striatal expression of genes responsible for neurotransmitter synthesis, neurotransmission, and signaling pathways implicated in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Function and regulation of CREB family transcription factors in the nervous system

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Isolation and characterization of PDE10A, a novel human 3', 5'-cyclic nucleotide phosphodiesterase

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Phosphodiesterases in the CNS: targets for drug development

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Overview of PDEs and their regulation

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

cGMP-dependent protein kinase type I promotes CREB/CRE-mediated gene expression in neurons of the lateral amygdala.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Role of phosphodiesterase 5 in synaptic plasticity and memory

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Immunohistochemical localization of PDE10A in the rat brain

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

A GluR1-cGKII interaction regulates AMPA receptor trafficking

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

The cell biology of synaptic plasticity: AMPA receptor trafficking

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

The role of phosphodiesterases in schizophrenia : therapeutic implications.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

The RIIbeta regulatory subunit of protein kinase A binds to cAMP response element: an alternative cAMP signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Alterations in gene regulation following inhibition of the striatum-enriched phosphodiesterase, PDE10A.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Regulation of CREB-mediated gene expression by salt inducible kinase

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Homologous involvement of striatum and prefrontal cortex in rodent and human water maze learning

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Requirement of TORC1 for late-phase long-term potentiation in the hippocampus

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

21 January 2018

Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FHIPO.22128

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HIPO.22128

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

ResearchGate publication ID

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