(Q45713668)

15 December 2017

title

Intrinsic translocation barrier as an initial step in pausing by RNA polymerase II. (English)

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15 December 2017

Masahiko Imashimizu

1

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15 December 2017

Maria L Kireeva

2

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15 December 2017

Lucyna Lubkowska

3

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15 December 2017

Deanna Gotte

4

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15 December 2017

Adam R Parks

5

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15 December 2017

Jeffrey N Strathern

6

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15 December 2017

Mikhail Kashlev

7

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15 December 2017

language of work or name

English

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publication date

10 December 2012

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Journal of Molecular Biology

15 December 2017

published in

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15 December 2017

volume

425

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15 December 2017

issue

4

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15 December 2017

page(s)

697-712

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The regulatory roles and mechanism of transcriptional pausing

15 December 2017

cites work

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12 December 2020

Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation

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12 December 2020

A Ratchet Mechanism of Transcription Elongation and Its Control

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12 December 2020

Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA

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A New Class of Bacterial RNA Polymerase Inhibitor Affects Nucleotide Addition

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12 December 2020

Tracking rates of transcription and splicing in vivo.

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12 December 2020

Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation

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12 December 2020

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

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12 December 2020

Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II.

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12 December 2020

A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing

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12 December 2020

Sequence-dependent kinetic model for transcription elongation by RNA polymerase

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12 December 2020

Molecular Basis of Transcriptional Mutagenesis at 8-Oxoguanine

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12 December 2020

Fast transcription rates of RNA polymerase II in human cells

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12 December 2020

Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution

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12 December 2020

RNA polymerase switches between inactivated and activated states By translocating back and forth along the DNA and the RNA.

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12 December 2020

The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes.

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12 December 2020

RNA transcript 3'-proximal sequence affects translocation bias of RNA polymerase

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12 December 2020

Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG.

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12 December 2020

Sequence-resolved detection of pausing by single RNA polymerase molecules.

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12 December 2020

Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes

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12 December 2020

Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS

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12 December 2020

Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals

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12 December 2020

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

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12 December 2020

Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage

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12 December 2020

Translocation by multi-subunit RNA polymerases.

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12 December 2020

Assays and affinity purification of biotinylated and nonbiotinylated forms of double-tagged core RNA polymerase II from Saccharomyces cerevisiae.

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12 December 2020

Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3' end of the RNA intact and extruded

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12 December 2020

Protein motors and Maxwell's demons: does mechanochemical transduction involve a thermal ratchet?

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12 December 2020

Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.

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12 December 2020

Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase

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12 December 2020

The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex

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12 December 2020

In vivo evidence for back and forth oscillations of the transcription elongation complex

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12 December 2020

The mechanism of nucleosome traversal by RNA polymerase II: roles for template uncoiling and transcript elongation factors

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12 December 2020

Elongation complexes of Thermus thermophilus RNA polymerase that possess distinct translocation conformations

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12 December 2020

Structural basis of RNA polymerase II backtracking, arrest and reactivation

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12 December 2020

Engineering of elongation complexes of bacterial and yeast RNA polymerases.

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12 December 2020

Transcript cleavage factors from E. coli.

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12 December 2020

Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase

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12 December 2020

Basic mechanisms of transcript elongation and its regulation

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12 December 2020

Transcription elongation through DNA arrest sites. A multistep process involving both RNA polymerase II subunit RPB9 and TFIIS.

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12 December 2020

Structural basis for substrate loading in bacterial RNA polymerase

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12 December 2020

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII

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12 December 2020

The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage

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12 December 2020

Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase

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12 December 2020

Active site opening and closure control translocation of multisubunit RNA polymerase

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12 December 2020

A thermodynamic analysis of RNA transcript elongation and termination in Escherichia coli

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12 December 2020

Shortening of RNA:DNA hybrid in the elongation complex of RNA polymerase is a prerequisite for transcription termination

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12 December 2020

The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin

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12 December 2020

Crucial role of the RNA:DNA hybrid in the processivity of transcription

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12 December 2020

RNA polymerase as a molecular motor

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12 December 2020

Recognition of the unique structure of DNA:RNA hybrids

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12 December 2020

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

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12 December 2020

Nascent transcript sequencing visualizes transcription at nucleotide resolution

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12 December 2020

Rapid kinetic analysis of transcription elongation by Escherichia coli RNA polymerase

1 reference

12 December 2020

Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner

1 reference

12 December 2020

Yeast Transcript Elongation Factor (TFIIS), Structure and Function

1 reference

12 December 2020

Interaction of a nascent RNA structure with RNA polymerase is required for hairpin-dependent transcriptional pausing but not for transcript release

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12 December 2020

Nature of the nucleosomal barrier to RNA polymerase II

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12 December 2020

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution

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12 December 2020

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability

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12 December 2020

Motion of RNA polymerase along DNA: a stochastic model

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12 December 2020

10.1016/J.JMB.2012.12.002

Identifiers

DOI

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15 December 2017

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