(Q45718626)

15 December 2017

title

Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. (English)

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15 December 2017

main subject

protein ubiquitination

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1 reference

Juan Liu

1

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15 December 2017

Chaofeng Han

2

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15 December 2017

Bin Xie

3

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15 December 2017

Yue Wu

4

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15 December 2017

Shuxun Liu

5

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15 December 2017

Kun Chen

6

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15 December 2017

Meng Xia

7

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15 December 2017

Yuan Zhang

8

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15 December 2017

Lijun Song

9

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15 December 2017

Zhiqing Li

10

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15 December 2017

Ting Zhang

11

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15 December 2017

Feng Ma

12

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15 December 2017

Qingqing Wang

13

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15 December 2017

Jianli Wang

14

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15 December 2017

Kejing Deng

15

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15 December 2017

Yuan Zhuang

16

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15 December 2017

Xiaohui Wu

17

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15 December 2017

Yizhi Yu

18

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15 December 2017

Tian Xu

19

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15 December 2017

Xuetao Cao

20

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15 December 2017

language of work or name

English

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publication date

25 May 2014

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15 December 2017

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15 December 2017

volume

15

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15 December 2017

issue

7

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15 December 2017

page(s)

612-622

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Recognition of microorganisms and activation of the immune response

15 December 2017

cites work

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Interleukin-17 and type 17 helper T cells

21 January 2018

1 reference

Regulatory T cells and immune tolerance

21 January 2018

1 reference

Th17 and regulatory T cells in mediating and restraining inflammation

21 January 2018

1 reference

IL-6: regulator of Treg/Th17 balance

21 January 2018

1 reference

The history of Toll-like receptors - redefining innate immunity.

21 January 2018

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

NF-κB and the link between inflammation and cancer

21 January 2018

1 reference

The role of dendritic cells in autoimmunity

21 January 2018

1 reference

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

1 reference

The rhomboid protease family: a decade of progress on function and mechanism

21 January 2018

1 reference

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases

21 January 2018

1 reference

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

21 January 2018

1 reference

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS

21 January 2018

1 reference

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

21 January 2018

1 reference

A large-scale functional approach to uncover human genes and pathways in Drosophila

21 January 2018

1 reference

Isolation and characterization of a novel pituitary tumor apoptosis gene

21 January 2018

1 reference

Ubiquitylation in innate and adaptive immunity.

21 January 2018

1 reference

Ubiquitination in signaling to and activation of IKK.

21 January 2018

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

21 January 2018

1 reference

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

21 January 2018

1 reference

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

1 reference

Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.

21 January 2018

1 reference

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

21 January 2018

1 reference

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains

21 January 2018

1 reference

A20: linking a complex regulator of ubiquitylation to immunity and human disease

21 January 2018

1 reference

Targeting Toll-like receptors: emerging therapeutics?

21 January 2018

1 reference

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response

21 January 2018

1 reference

Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

21 January 2018

1 reference

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

21 January 2018

1 reference

Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3.

21 January 2018

1 reference

CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation

21 January 2018

1 reference

Not just a sink: endosomes in control of signal transduction

21 January 2018

1 reference

ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system

21 January 2018

1 reference

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation

21 January 2018

1 reference

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

21 January 2018

1 reference

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

21 January 2018

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

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Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis.

21 January 2018

1 reference

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

21 January 2018

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Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20

21 January 2018

1 reference

Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway

21 January 2018

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Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation

21 January 2018

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Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

21 January 2018

1 reference

Chemically induced mouse models of intestinal inflammation

21 January 2018

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TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24859449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SOCS-1 participates in negative regulation of LPS responses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24859449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2898

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15 December 2017

1 reference