(Q45858962)

17 December 2017

title

Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9. (English)

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17 December 2017

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5

In-Hyun Park

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17 December 2017

author name string

Chul-Yong Park

1

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17 December 2017

Jin Jea Sung

2

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17 December 2017

Sang-Hwi Choi

3

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17 December 2017

Dongjin R Lee

4

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17 December 2017

Dong-Wook Kim

6

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17 December 2017

language of work or name

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6 October 2016

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17 December 2017

published in

Nature Protocols

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17 December 2017

volume

11

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17 December 2017

issue

11

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17 December 2017

page(s)

2154-2169

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17 December 2017

describes a project that uses

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

The promise of induced pluripotent stem cells in research and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Feeder-independent culture of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A TALE nuclease architecture for efficient genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Double-strand break end resection and repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome structural variation discovery and genotyping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Structural variation in the human genome and its role in disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Phenotypic impact of genomic structural variation: insights from and for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Chromosomal translocation engineering to recapitulate primary events of human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome Editing of Structural Variations: Modeling and Gene Correction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A guide to genome engineering with programmable nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Rationally engineered Cas9 nucleases with improved specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

In vivo genome editing using Staphylococcus aureus Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Therapeutic genome editing: prospects and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Induced Pluripotent Stem Cells Meet Genome Editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

CRISPR-mediated direct mutation of cancer genes in the mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

From mouse to man: generating megabase chromosome rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Chromosomal translocations induced at specified loci in human stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Targeted chromosomal deletions in human cells using zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient TALEN-mediated gene knockout in livestock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Multiple genome modifications by the CRISPR/Cas9 system in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Highly efficient multiplex targeted mutagenesis and genomic structure variation in Bombyx mori cells using CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Shortening trinucleotide repeats using highly specific endonucleases: a possible approach to gene therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Diseases of unstable repeat expansion: mechanisms and common principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Tandem repeat modification during double-strand break repair induced by an engineered TAL effector nuclease in zebrafish genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Cancer translocations in human cells induced by zinc finger and TALE nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Chimeric nucleases stimulate gene targeting in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

In situ genetic correction of F8 intron 22 inversion in hemophilia A patient-specific iPSCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Manipulating the mammalian genome by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome engineering using the CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Generation of human induced pluripotent stem cells from urine samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Surrogate reporters for enrichment of cells with nuclease-induced mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A more efficient method to generate integration-free human iPS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

A rapid and general assay for monitoring endogenous gene modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Genome Editing in Human Cells Using CRISPR/Cas Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

TALEN- and CRISPR/Cas9-Mediated Gene Editing in Human Pluripotent Stem Cells Using Lipid-Based Transfection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

CRISPR/Cas9-Directed Genome Editing of Cultured Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Characterization of pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Targeted genomic rearrangements using CRISPR/Cas technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Generation and characterization of human induced pluripotent stem cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2016.129

Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27711053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPROT.2016.129

1 reference

17 December 2017

Dimensions Publication ID

1032721397

0 references

1 reference

17 December 2017