(Q45883899)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents (English)

1 reference

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21 February 2020

3

1 reference

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21 February 2020

6

Michael P Manns

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Ina Rittelmeyer

1

1 reference

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21 February 2020

Michael Rothe

2

1 reference

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21 February 2020

Marcus Iken

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Axel Schambach

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Christopher Baum

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Ute Modlich

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Michael Ott

9

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

27 May 2013

1 reference

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21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

58

1 reference

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21 February 2020

issue

1

1 reference

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21 February 2020

page(s)

397-408

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23258554%20AND%20SRC:MED&resulttype=core&format=json

Retroviral vector-mediated gene therapy for metabolic diseases: an update

21 February 2020

cites work

1 reference

Safety and feasibility of liver-directed ex vivo gene therapy for homozygous familial hypercholesterolemia.

21 January 2018

1 reference

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

21 January 2018

1 reference

Clinical application of lentiviral vectors - concepts and practice

21 January 2018

1 reference

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

21 January 2018

1 reference

Epidermal growth factor improves lentivirus vector gene transfer into primary mouse hepatocytes

21 January 2018

1 reference

Therapeutic lentivirus-mediated neonatal in vivo gene therapy in hyperbilirubinemic Gunn rats

21 January 2018

1 reference

Neonatal gene therapy of glycogen storage disease type Ia using a feline immunodeficiency virus-based vector

21 January 2018

1 reference

Hematopoietic stem cell engineering at a crossroads

21 January 2018

1 reference

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

21 January 2018

1 reference

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

21 January 2018

1 reference

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

21 January 2018

1 reference

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

21 January 2018

1 reference

Transcription start regions in the human genome are favored targets for MLV integration

21 January 2018

1 reference

Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors

21 January 2018

1 reference

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

21 January 2018

1 reference

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 January 2018

1 reference

Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells

21 January 2018

1 reference

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

21 January 2018

1 reference

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

21 January 2018

1 reference

Lentiviral vector induced insertional haploinsufficiency of Ebf1 causes murine leukemia

21 January 2018

1 reference

Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice

21 January 2018

1 reference

Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.

21 January 2018

1 reference

Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

21 January 2018

1 reference

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.

21 January 2018

1 reference

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

21 January 2018

1 reference

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

21 January 2018

1 reference

Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples

21 January 2018

1 reference

Retroviral insertion site analysis in dominant haematopoietic clones

21 January 2018

1 reference

Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.

21 January 2018

1 reference

Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

21 January 2018

1 reference

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

21 January 2018

1 reference

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

21 January 2018

1 reference

Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples

21 January 2018

1 reference

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

21 January 2018

1 reference

A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector

21 January 2018

1 reference

Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: implications for gene therapy

21 January 2018

1 reference

AAV vector integration sites in mouse hepatocellular carcinoma.

21 January 2018

1 reference

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.

21 January 2018

1 reference

Assessing the potential for AAV vector genotoxicity in a murine model

21 January 2018

1 reference

Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.

21 January 2018

1 reference

Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

21 January 2018

1 reference

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

21 January 2018

1 reference

RGB marking facilitates multicolor clonal cell tracking

21 January 2018

1 reference

Murine leukemia induced by retroviral gene marking

21 January 2018

1 reference

7 January 2021

Quantifying growth and transformation frequency of oncogene-expressing mouse hepatocytes in vivo

1 reference

7 January 2021

Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells

1 reference

7 January 2021

Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16

1 reference

7 January 2021