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Hematopoietic stem cell engineering at a crossroads
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Europe PubMed Central
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3277348
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16 January 2020
title
Hematopoietic stem cell engineering at a crossroads
(English)
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PubMed
stated in
Europe PubMed Central
PMCID
3277348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
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16 January 2020
author
Cynthia E. Dunbar
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2
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3277348
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16 January 2020
author name string
Isabelle Rivière
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1
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Europe PubMed Central
PMCID
3277348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
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16 January 2020
Michel Sadelain
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3
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3277348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
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16 January 2020
language of work or name
English
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publication date
17 November 2011
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retrieved
16 January 2020
published in
Blood
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
119
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PubMed
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
5
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PubMed
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
1107-1116
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Europe PubMed Central
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3277348
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
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16 January 2020
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Genomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Stem cell engineering for the treatment of severe hemoglobinopathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Reduced genotoxicity of avian sarcoma leukosis virus vectors in rhesus long-term repopulating cells compared to standard murine retrovirus vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Strategies and new developments in the generation of patient-specific pluripotent stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
The genetic engineering of hematopoietic stem cells: the rise of lentiviral vectors, the conundrum of the ltr, and the promise of lineage-restricted vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Genotoxicity of retroviral integration in hematopoietic cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Foamy virus vector integration sites in normal human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Silencing and variegation of gammaretrovirus and lentivirus vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Genome-wide analysis of retroviral DNA integration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Culture and characterization of human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Occurrence of leukaemia following gene therapy of X-linked SCID.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Triplex forming oligonucleotides: sequence-specific tools for gene targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Gene therapy for genetic haematological disorders and immunodeficiencies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Hematopoietic stem cell gene therapy: towards clinically significant gene transfer efficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Gene silencing as a threat to the success of gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Transduction of hematopoietic cells by foamy virus vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Gene transfer to hematopoietic stem cells: implications for gene therapy of human disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 September 2017
An inducible caspase 9 safety switch for T-cell therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
31 May 2018
Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
31 May 2018
Genetic treatment of severe hemoglobinopathies: the combat against transgene variegation and transgene silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
31 May 2018
Safe harbours for the integration of new DNA in the human genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
TALEs of genome targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Chromatin boundaries, insulators, and long-range interactions in the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Blood stem cells emerge from aortic endothelium by a novel type of cell transition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Modeling disease in human ESCs using an efficient BAC-based homologous recombination system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Gene therapy fulfilling its promise
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Granulocyte colony-stimulating factor-based stem cell mobilization in patients with sickle cell disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Efficient transduction and engraftment of G-CSF-mobilized peripheral blood CD34+ cells in nonhuman primates using GALV-pseudotyped gammaretroviral vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
FMEV vectors: both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277348
retrieved
28 November 2018
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22096239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reversal of early neurologic and neuroradiologic manifestations of X-linked adrenoleukodystrophy by bone marrow transplantation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22096239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22096239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22096239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Eliminating cells gone astray
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22096239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/BLOOD-2011-09-349993
1 reference
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMCID
3277348
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed ID
22096239
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
3277348
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22096239%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
ResearchGate publication ID
51808317
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