(Q45923687)

17 December 2017

title

Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia. (English)

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17 December 2017

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3

Paul Greengard

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17 December 2017

Emmanuel Valjent

4

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Myriam Heiman

series ordinal

2

object named as

Myriam Heiman

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17 December 2017

author name string

Emanuela Santini

series ordinal

1

1 reference

17 December 2017

Gilberto Fisone

series ordinal

5

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17 December 2017

publication date

21 July 2009

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17 December 2017

published in

Science Signaling

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17 December 2017

volume

2

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17 December 2017

issue

80

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17 December 2017

page(s)

ra36

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17 December 2017

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

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L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

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Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia

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Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.

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11 October 2022

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Parkinson's disease: levodopa-induced dyskinesia and signal transduction.

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Rheb binds and regulates the mTOR kinase

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11 October 2022

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The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease

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11 October 2022

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11 October 2022

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Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation

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11 October 2022

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RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.

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11 October 2022

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11 October 2022

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Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications

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11 October 2022

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Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.

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11 October 2022

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11 October 2022

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D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

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11 October 2022

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RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

MAPK cascade signalling and synaptic plasticity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCISIGNAL.2000308

Identifiers

DOI

10.1126/SCISIGNAL.2000308

1 reference

17 December 2017

1 reference

17 December 2017